Fragile X Syndrome: Diagnosis, Treatment, and ResearchRandi Jenssen Hagerman, Paul J. Hagerman Fragile X syndrome is the most common inherited form of mental retardation. Now substantially revised and updated, this acclaimed book discusses the clinical approach to diagnosing the disorder, supported by the latest research in epidemiology, molecular biology and genetics, and neuropsychology. It also presents information on treatment: genetic counseling, pharmacotherapy, intervention, and gene therapy. |
Contents
The Physical and Behavioral Phenotype | 3 |
The Molecular Biology of the Fragile X Mutation | 110 |
Epidemiology | 136 |
FMR1 Protein Studies and Animal Model for Fragile X Syndrome | 169 |
Brain Structure and the Functions of FMR1 Protein | 191 |
Neuropsychology | 206 |
Treatment and Intervention | 249 |
Genetic Counseling | 251 |
An Integrated Approach to Intervention | 363 |
Academic Interventions | 428 |
FMR1 Gene Expression and Prospects for Gene Therapy | 465 |
General Information about Fragile X Syndrome | 495 |
Computer Software Information | 501 |
Learning Materials and Equipment | 514 |
Toilet Training the Child with Fragile X Syndrome | 527 |
| 531 | |
Medical Followup and Pharmacotherapy | 287 |
The Treatment of Emotional and Behavioral Problems | 339 |
Other editions - View all
Fragile X Syndrome: Diagnosis, Treatment, and Research Randi Jenssen Hagerman,Paul J. Hagerman Limited preview - 2002 |
Common terms and phrases
abnormalities Acad activity ADHD adult alleles anxiety autism B. A. Oostra behavior boys with FXS brain cells CGG repeat chap Child Adolesc child with FXS children with FXS chromosome Clin clinical clonidine cognitive cytogenetic D. L. Nelson dendritic dendritic spines developmental diagnosis disabilities disorder drome effects females with FXS fluoxetine FMR1 FMRI FMRI gene FMRP folic acid fragile X syndrome Fryns full mutation function genetic counseling hyperactivity individuals with FXS intervention language learning levels macroorchidism males with fragile males with FXS Mazzocco medication Ment mental retardation methylation methylphenidate mice molecular motor mRNA neurons neuropsychologic normal patients with FXS Pediatr phenotype premature ovarian failure premutation carriers prenatal problems protein Psychiatry R. J. Hagerman Reiss reported S. T. Warren sensory skills Sobesky social specific studies Tassone testing therapy tion tissue treatment visual W. T. Brown women X-linked mental retardation
Popular passages
Page 492 - Schwarze, SR, Ho, A., Vocero-Akbani, A., and Dowdy, SF (1999) In vivo protein transduction: delivery of a biologically active protein into the mouse.