Robert M. Simmons
Cambridge University Press, Jun 26, 1992 - Medical - 299 pages
Composed of a set of chapters contributed by past and present collaborators of the Nobel laureate Sir Andrew Huxley, this book covers the areas of muscle research to which Huxley made major contributions. The purpose of the book is to discuss the way that muscles work, asking questions at a fundamental level about the molecular basis of muscle tone production and muscle contraction. The majority of the chapters are concerned with muscle physiology and the relation between structure and function. The process of activation of muscles is discussed, along with the mechanism of contraction itself. Although most of the book deals with vertebrate skeletal muscle, several chapters cover cardiac muscle. Also featured are two chapters discussing Sir Andrew's achievements in both nerve and muscle physiology.
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A F Huxleys research on muscle Robert M
Ultraslow slow intermediate and fast inactivation
The calciuminduced calcium release mechanism in
Hypodynamic tension changes in the frog heart
Regulation of contractile proteins in heart muscle
Highspeed digital imaging microscopy of isolated
Inotropic mechanism of myocardium Lincoln E
dual role of
Fibre types in Xenopus muscle and their
Structural changes accompanying mechanical
Mechanochemistry of negatively strained cross
Force response in steady lengthening of active
A. F. Huxley actin action potential Andrew Huxley ATPase activity attached cross-bridges axon Biophysical Ca2+ caffeine calcium binding calcium release channel calcium-induced calcium release cardiac concentration contractile contracture cross-bridge attachment decrease depolarisation detachment e-c coupling effect electron Endo enhanced experiments fatigue filament overlap force force-extension Ford Franzini-Armstrong frog function Goldman Gonzalez-Serratos Gordon heart Hodgkin Hugh Huxley inactivation increase ions isometric isotonic Journal of Physiology Lannergren length change lengthening London measured membrane ments microscopy muscle cells muscle contraction muscle fibres myoballs myofibrils myosin negative strain nerve fibres Niedergerke nm per h.s. obtained Peachey Podolsky proteins records recovery relaxation response Riidel Ringer's saltatory conduction sarcomere length sarcoplasmic reticulum shortening velocity showed Simmons skeletal muscle skinned fibres slow sodium step stiffness stimulation stretch striated muscle striation spacing structure studies T-tubule tension transients tetanised tetanus thin filament tion tropomyosin troponin types wavy myofibrils Z-line
Page 261 - Ca2+ on cross-bridge turnover kinetics in skinned single rabbit psoas fibers: implications for regulation of muscle contraction Proc.