Human Biochemistry and DiseaseThis textbook is specifically designed for upper-division undergraduate or graduate students in life science or pre-medical majors including dentistry or pharmacology, who are required to take a biochemistry or medical biochemistry course, but who are not necessarily biochemistry majors. The book adopts a unique approach to the topic compared with other biochemistry textbooks currently available, in that each biochemical subject is introduced by a human disease relating the biochemical principles to be developed in that chapter. The goal is to make biochemistry more meaningful to the student who is not normally shown the connection between biochemistry and medicine.
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Contents
| 1 | |
| 33 | |
| 93 | |
Chapter 4 Carbohydrates | 131 |
Chapter 5 Lipids | 189 |
Chapter 6 Nucleic Acids and Molecular Genetics | 239 |
Chapter 7 Transcription | 323 |
Chapter 8 Polypeptide Hormones | 365 |
Chapter 12 Membrane Transport | 685 |
Chapter 13 Dietary Metals Iron Micronutrients and Nutrition | 739 |
Chapter 14 Blood and Lymphatic System | 853 |
Chapter 15 Immunobiochemistry | 899 |
Chapter 16 Neurobiochemistry | 955 |
Chapter 17 Microbial Biochemistry | 1047 |
Appendices | 1153 |
Glossary | 1159 |
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Common terms and phrases
acetyl CoA active aldosterone amino acid amino acid residues anandamide antibody antigen apoptosis aspartate binding Biol bond Ca2+ calcium carbon caspases catalyzed cell membrane CH2 CH2 chain channel cholesterol citric acid cycle coenzyme complex converted COOH COOJ cortisol Crystal structure cycle cytokine cytoplasm decarboxylase dehydrogenase dimer disease domain enzyme extracellular fatty acid gene glucagon glucocorticoid glucose glutamate glutamine glycogen growth factor heme hemoglobin histone inhibition inhibitor insulin interaction intestine ligand lipid liver metabolism mitochondrion Molecular molecules mRNA muscle neuron nucleus OH OH oxidation oxygen pathway PDB ID peptide phosphate phosphorylation pituitary plasma produced protein kinase pyruvate reaction receptor release Reproduced from Figure reproduced from PDB ribosome secretion sequence serine shown in Figure signal stimulates strand structure of human substrate subunit synthase synthesis synthetase thyroid tion tissues transcription transmembrane transport tyrosine vitamin