Immunology: A Short CourseImmunology: A Short Course, Sixth Edition introduces all the critical topics of modern immunology in clear and succinct yet comprehensive fashion. The authors offer a uniquely balanced coverage of classical and contemporary approaches, basic and clinical aspects. As with the previous editions, the strength of the text is in a complete review of modern immunology without burdening the reader with excessive data or theoretical discussions. Each chapter is divided into short, self-contained units that address key topics illustrated by uniformly drawn, full-color illustrations, many brand new to this edition. The sixth edition of this successful textbook newly covers:
Praise for the previous edition: "This book is clearly a precious resource for undergraduate, graduate and medical students alike… For those who need an introduction to the fascinating world of immunology, this book should most certainly spark the interest." "… an excellent beginner's guide… the authors have done a terrific job of providing an overview of the field." |
Contents
ELEMENTS OF INNATE AND ACQUIRED | 11 |
IMMUNOGENS AND ANTIGENS | 29 |
ANTIBODY STRUCTURE AND FUNCTION | 41 |
5 | 61 |
THE GENETIC BASIS OF ANTIBODY | 81 |
BIOLOGY OF THE B LYMPHOCYTE | 93 |
ROLE OF THE MAJOR HISTOCOMPATIBILITY | 107 |
BIOLOGY OF THE T LYMPHOCYTE | 125 |
ACTIVATION AND FUNCTION | 141 |
Autoimmune Diseases in Which T Cells Play | 198 |
Examples of DTH | 249 |
AND NEOPLASIAS OF THE LYMPHOID SYSTEM | 255 |
Common terms and phrases
amino acids anti antibody antigen antigen-specific apoptosis associated autoimmune diseases autoreactive bacteria bind blood bone marrow CD4+ T cells CD8+ cell surface cells expressing cellular Chapter chemokine class I molecules complement activation coreceptor costimulatory cytotoxic dendritic cells described differentiation enzymes epitope factor Figure function gene segments H-chain heavy chains host cells hypersensitivity Ig molecules immune complexes immune response immune system immunogenic immunoglobulin Immunol immunologic individual induce infection innate immune interaction intracellular involved isotype ligand light chains lymph nodes lymphocytes lymphoid organs macrophages mast cells mechanisms mediated membrane MHC class MHC class II MHC molecules mice molecules neutrophils NK cells pathogens patients peptides phagocytic phagocytosis plasma cells produced protein reactions rearrangement region release result role self-antigen serum signal specific subset synthesized T-cell responses target cell TH17 cells thymic thymus tion tissue Treg tumor cells vaccine viral virus viruses