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activity allele amino acid analysis antigen binding Biochem Biol breeding cells chromatin chromo chromosome coll complex components cone correlated culture cytoplasmic decreased density detected differentiation diploid disease DNA replication DNA synthesis E.coli effect enzyme Escherichia coli factors fraction frequency gene genetic genome growth histone Hosp hybrid incorporation increase incubation indicate induced infected inhibition inhibitor Inst irradiation isolated karyotype labeled liver lymphocytes membrane metabolism methyl mice mitosis mol wt molecules mouse mRNA mutants normal nuclear nuclei nucleic acid nucleotide observed oocytes patients pattern phage phenotype plants poly polysomes population present production protein synthesis replication resistance ribosomes RNA polymerase rRNA sedimentation selection sensitive sequence serum showed specific strs structure studied subunits suggested syndrome temp template thymidine tion tissue treatment tRNA Univ USSR viral virus vitro vivo wild-type yeast