Advanced Dairy Chemistry: Volume 1: Proteins, Parts A&B: Protein

Front Cover
P. F. Fox, P. L. H. McSweeney
Springer Science & Business Media, 2003 - Medical - 1346 pages
Advanced Dairy Chemistry-1. Proteins addresses the most commercially important constituents of milk in terms of their roles in nutrition and as functional components in foods. This third edition, which is the work of dairy scientists and other experts from around the world, provides detailed scientific information on all aspects of milk proteins.An extensively revised Table of Contents includes more chapter-level headings to make the material more accessible and highlights a number of key topics, such as methods for resolving and identifying proteins, biologically and physiologically active proteins, molecular genetics and functional milk proteins-all of which have assumed increased importance in recent years.All chapters from the second edition have been completely updated and coverage of the biological properties and stability of milk proteins has been enhanced greatly. The book has been expanded from 18 chapters in the second edition to 29 chapters and is divided into two parts: Part A (Chapters 1-11) describes the more basic aspects of milk proteins, while Part B (Chapters 12-29) reviews the more applied aspects. New topics include an overview of the milk protein system, allergenicity of milk proteins, bioactive peptides, genetic engineering of milk proteins, and certain additional chapters on protein-rich dairy products.This authoritative work summarizes current knowledge on milk proteins and suggests areas for future work.
 

Contents

Milk proteins general and historical aspects
1
12 Preparation of casein and why proteins
5
13 Comparison of key properties of casein and whey proteins
9
14 Heterogeneity and fractionation of casein
11
15 Application of gel electrophoresis to the study of milk proteins
14
16 Microheterogeneity of the caseins
15
17 Nomenclature of milk proteins
18
19 Fractionation of whey proteins
19
𝛼Lactalbumin
387
82 OVERVIEW OF EARLIER WORK
388
83 Structure
392
84 Aspects of 𝛼lactalbumin function
401
85 Conclusion
410
Acknowledgement
412
Immunoglobulins
421
93 Transfer of passive immunity
431

110 Some major characteristics of why proteins
20
111 Molecular properties of the milk proteins
28
112 Casein micelle
31
113 Interspecies comparison of milk products
39
114 Summary and perspective
40
References
41
Quantitation of proteins in milk and milk products
49
21 Introduction
51
22 Definitions of protein and analytical performance
52
23 Reference and routine methods
56
24 Separate deterimination and characterization of individual proteins in milk and dairy products
80
25 Immunochemicals methods
106
References
119
Chemistry of caseins
139
32 Protein composition of milk
140
33 Isolation and identification of caseins
145
34 Primary structure and chemical composition of the caseins
154
35 Physicochemical characteristics of the caseins
176
36 Projection of future work
187
Higher orders structures of the caseins a paradox?
203
42 Molecular modelling of aₓ₁
211
43 The tensegrity hypothesis and resolution
225
References
229
Casein micelle structure functions and interactions
233
52 Biological functions of the caseins
234
53 Structure of the individual caseins
236
54 Size and voluminosity of the casein micelle
241
55 Surface structure of the casein micelle
244
56 Internal structure of the casein micelle
246
57 Dissociation of casein micelles in response to environmental change
254
58 Aggregation gelation and syneresis
258
Acknowledgements
270
Nonbovine caseins quantitative variability and molecular diversity
277
62 The casein gene locus and quantitative variability
278
an interspecies comparison
281
interspecies variability
289
65 Micelle organisation
301
66 Analytical tools
303
67 Concluding remarks
308
References
310
𝛽Lactoglobulin
319
72 Biosynthesis and secretion
320
73 Distribution
321
74 Isolation
324
75 Genetic variants and primary structure
325
76 Molecular structure
330
77 Solution studies
335
78 Denaturation
337
79 Secondary structure
342
711 Amino acid environments
345
712 Sitedirected mutagenesis
347
713 Binding studies
348
714 Homologous proteins
358
715 Function
361
716 Conclusion
363
94 Control of transport and mammary gland immunity
436
95 Interactions with other proteins in milk
437
97 Conclusion
438
References
439
Lactoferrin
449
103 Molecular biology of lactoferrin
452
104 Biological functions of lactoferrin
453
105 Lactoferrin receptors
459
106 Implications and significance
461
Indigenous enzymes in milk
467
References
470
Lipases in milk
473
1122 Role of the lipoprotein lipase in metabolism of plasma lipoproteins
474
1123 Structure
475
1124 Catalytic properties
479
1125 Apolipoprotein CII
480
1126 Product inhibition
481
1128 LPL in the mammary gland
483
1129 SYNTHESIS AND SECRETION INTO MILK
484
11210 State of LPL in milk
486
11211 Lipolysis in milk
487
References
488
Indigenous proteinases in milk
495
1132 Plasmin system in milk
496
1133 Somatic cell proteinases
505
References
512
Indigenous phosphates in milk
523
1142 Acid phosphatase
525
1143 Milk alkaline phosphatase
530
References
539
Indigenous nucleases in milk
545
1153 Ribonucleases
547
1154 Ribonucleases in milk
549
1155 Catalytic antibodiesabyzmes with oligonuclease activity
552
References
557
Lactoperoxidase
563
1162 Structure of bovine lactoperoxidase bLPO
564
1163 Major reactions of bovine lactoperoxidase
566
1164 Components of the lactoperoxidase system in bovine milk
567
1166 Conclusions
568
Other enzymes 1171 Introduction
571
1173 Catalase EC 11116
572
1174 Glutathione peroxidase EC 11119
574
1176 Xanthine oxidase EC 11322
576
1177 Sulphydryl oxidase
578
1178 YGlutamyl transferase EC 2322
579
1179 Amylases
580
11710 Lysozyme EC 32117
581
11711 NAcetyl𝛽Dglucosaminidase EC 32130
583
11712 𝛼Mannosidase EC 32124
584
11714 5Nucleotidase EC 3135
585
11715 Adenosine triphosphatase EC 3613
586
11717 Other enzymes
591
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