CELLULAR AND MOLECULAR IMMUNOLOGY

activated B cells adaptive immune response adaptor affinity amino acids antibody molecules antigen binding antigen receptor antigen-presenting cells antimicrobial autoimmune diseases bacteria blood bone marrow cause CD4+ CD8+ cell activation cell surface chemokines class II MHC complement complex components costimulators costimulatory cytokines cytoplasmic cytosolic dendritic cells differentiation domains effector enzymes epithelial expression function genes germinal centre heavy chain helper T cells humoral immune identify immune system immunoglobulin immunological infections innate immune response interaction intracellular isotype ITAM ligands light chains lymph nodes lymphocytes macrophages maturation mediated MHC molecules mice microbes molecular molecules mutations neutrophils NK cells PAMPs pathogens pathways pattern recognition receptors peptides peripheral phagocytes phagocytosis phosphorylated plasma cells plasma membrane produced proliferation protein antigens PRRs reaction regions residues role secreted self-antigens self-reactive signalling specific T-cells target thymus tissues TLRs tolerance Toll-like receptors transcription factors trigger vaccine viruses zone