Clarke's Isolation and Identification of Drugs in Pharmaceuticals, Body Fluids, and Post-mortem Material
Pharmaceutical Press, 1986 - Drug adulteration - 1223 pages
This practical manual and standard reference work provides an authoritative source of analytical data for drugs and related substances. It is intended for scientists faced with the difficult problem of identifying an unknown drug in a pharmaceutical product, in a sample of tissue or body fluid from a living patient or in postmortem material. It is intended to be a useful requirement for all forensic and crime laboratories, toxicologists, clinical and analytical chemists, pathologists, poison information centres and clinical pharmacology departments.
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350 Wavelength Absorbance absorption acid administration analysis analytical applied Aqueous blood Body chloride chloroform Chromat Clin Colour Tests column compounds containing daily detection dilute Disposition DISTRIBUTION dose drug effects et al ethanol ether extract fatalities GA-RI Gas Chromatography give given glucuronic acid half-life High Pressure Liquid hydrochloride increased indicates Infra-red Spectrum ingestion injection KBr disk less limit Mass Spectrum material measured metabolites method minutes ng/ml obtained occur peaks at m/z peaks at wavenumbers phase plasma concentrations plate poisoning positive practically insoluble preparation presence Pressure Liquid Chromatography Principal peaks produce Proprietary Names Quantification range reagent reference relative reported sample sensitivity separate serum single sodium soluble soluble in water solution solvent spectra standard subjects Synonym System TA-Rf THERAPEUTIC Thin-layer Chromatography tion tissue toxic Transmittance ug/ml Ultraviolet Spectrum unchanged urine usually values volume yellow