DNA Repair and Mutagenesis

DNA Repair and Mutagenesis is an extremely comprehensive and current text covering the manifold ways in which living cells respond to genomic injury and alterations, including both spontaneous and environmentally induced DNA damage.

This book begins with a discussion of the phenomena of DNA damage and mutagenesis and then systematically explores all of the known DNA repair and other cellular response modes in prokaryotes and eukaryotes, including mammalian cells. A major feature of this edition is the comprehensive coverage of mutagenesis and other aspects of DNA damage tolerance. The final chapter is devoted to a discussion of known human diseases and disease syndromes with defective cellular responses to DNA damage.