Emission Tomography: The Fundamentals of PET and SPECT

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Elsevier, Dec 7, 2004 - Medical - 596 pages
PET and SPECT are two of today’s most important medical-imaging methods, providing images that reveal subtle information about physiological processes in humans and animals. Emission Tomography: The Fundamentals of PET and SPECT explains the physics and engineering principles of these important functional-imaging methods. The technology of emission tomography is covered in detail, including historical origins, scientific and mathematical foundations, imaging systems and their components, image reconstruction and analysis, simulation techniques, and clinical and laboratory applications. The book describes the state of the art of emission tomography, including all facets of conventional SPECT and PET, as well as contemporary topics such as iterative image reconstruction, small-animal imaging, and PET/CT systems. This book is intended as a textbook and reference resource for graduate students, researchers, medical physicists, biomedical engineers, and professional engineers and physicists in the medical-imaging industry. Thorough tutorials of fundamental and advanced topics are presented by dozens of the leading researchers in PET and SPECT. SPECT has long been a mainstay of clinical imaging, and PET is now one of the world’s fastest growing medical imaging techniques, owing to its dramatic contributions to cancer imaging and other applications. Emission Tomography: The Fundamentals of PET and SPECT is an essential resource for understanding the technology of SPECT and PET, the most widely used forms of molecular imaging.

*Contains thorough tutorial treatments, coupled with coverage of advanced topics
*Three of the four holders of the prestigious Institute of Electrical and Electronics Engineers Medical Imaging Scientist Award are chapter contributors
*Include color artwork
 

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Contents

Chapter 1 Imaging Science Bringing the Invisible to Light
1
Chapter 2 Introduction to Emission Tomography
11
Chapter 3 Evolution of Clinical Emission Tomography
25
Chapter 4 Basic Physics of Radioisotope Imaging
53
Chapter 5 Radiopharmaceuticals for Imaging the Brain
89
Chapter 6 Basics of Imaging Theory and Statistics
103
Chapter 7 SinglePhoton Emission Computed Tomography
127
Chapter 8 Collimator Design for Nuclear Medicine
153
Chapter 15 CdTe and CdZnTe Semiconductor Detectors for Nuclear Medicine Imaging
269
Chapter 16 ApplicationSpecific Small FieldofView Nuclear Emission Imagers in Medicine
293
Chapter 17 Intraoperative Probes and Imaging Probes
335
Chapter 18 Noble Gas Detectors
359
Chapter 19 Compton Cameras for Nuclear Medical Imaging
383
Chapter 20 Analytic Image Reconstruction Methods
421
Chapter 21 Iterative Image Reconstruction
443
Chapter 22 Attenuation Scatter and Spatial Resolution Compensation in SPECT
473

Chapter 9 Annular SingleCrystal SPECT Systems
169
Chapter 10 PET Systems
179
Chapter 11 PETCT Systems
195
Chapter 12 Small Animal PET Systems
213
Chapter 13 Scintillators
229
Chapter 14 Photodetectors
255
Chapter 23 Kinetic Modeling in Positron Emission Tomography
499
Chapter 24 Computer Analysis of Nuclear Cardiology Procedures
541
Chapter 25 Simulation Techniques and Phantoms
551
Index
565
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Page 2 - While it is never safe to affirm that the future of Physical Science has no marvels in store even more astonishing than those of the past, it seems probable that most of the grand underlying principles have been firmly established and that further advances are to be sought chiefly in the rigorous application of these principles to all the phenomena which come under our notice.
Page 8 - As far as the laws of mathematics refer to reality, they are not certain; and as far as they are certain, they do not refer to reality.
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Page 537 - Positron emission tomography and autoradiography: principles and applications for the brain and heart.
Page 537 - Quantitative measurement of local cerebral blood flow in humans by positron computed tomography and 15O-water / Cereb Blood Flow Metab 3, 141-153.
Page 1 - ... indication of this is the delight we take in our senses; for even apart from their usefulness they are loved for themselves; and above all others the sense of sight. For not only with a view to action, but even when we are not going to do anything, we prefer seeing (one might say) to everything else. The reason is that this, most of all the senses, makes us know and brings to light many differences between things.
Page 539 - Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data.

About the author (2004)

Wernick, Departments of Electrical and Computer Engineering and Biomedical Engineering, Illinois Institute of Technology, and Predictek, LLC, Chicago.

Aarsvold, Nuclear Medicine Service, Atlanta VA Medical Center, Decatur, GA

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