Foundations of Anesthesia: Basic Sciences for Clinical Practice118 international experts provide you with complete coverage of basic and clinical science in anesthesiology. They emphasize the principles and clinical applications of molecular and cell biology, physiology, pharmacology, and physics and measurement. Over 700 full-color illustrations and easy-to-read tables and graphs help you understand every detail. Uses a visual approach with excellent full-color line illustrations. Includes a bonus CD-ROM that allows you to download all of the book's figures into PowerPoint® for electronic presentations. Refers only to key references from primary papers keeping information that is the most up-to-date. Contains new chapters on: Adverse Drug Reactions (Ch. 10), Sensory Systems (Ch. 22), Physiology of Pain (Ch. 23), Mechanisms of Anesthesia (Ch. 24), Consciousness & Cognition (Ch.29), Sleep & Anesthesia (Ch. 30), and Physiology & Pharmacology of Blood Coagulation (Ch. 53). Includes increased coverage of ultrasound in anesthesiology and clinical care. Offers new information on genomics and proteomics. Shows "clinical pearls" boxes in every chapter for added speed in reference. With 115 additional contributors |
Contents
General Principles | 1 |
hemodynamic monitoring | 173 |
xv | 189 |
Statistics | 207 |
Biology of the cell | 216 |
Sleep and anesthesia | 219 |
The synapse | 233 |
71 | 257 |
Pharmacology of local anesthetics | 393 |
Muscle | 419 |
Blood constituents and transfusion | 625 |
muscle reflexes and control of movement | 647 |
Neuromuscular junction physiology | 659 |
Neuromuscular junction pharmacology | 671 |
Xueqin Ding and Paul A Murray | 685 |
Renal pathophysiology | 699 |
79 | 267 |
mechanisms | 287 |
Intravenous anesthetic agents | 295 |
Adverse drug reactions | 311 |
Pharmacokinetics of inhalation | 323 |
143 | 337 |
Electrophysiological monitoring | 349 |
Ralph Lydic and Helen A Baghdoyan | 361 |
Opioids | 373 |
Nonopioid analgesic | 385 |
Jeffrey R Balser and Annemarie Thompson | 709 |
David F Stowe | 723 |
The peripheral circulation | 737 |
Nikolaos Skubas and Stephen J Thomas | 753 |
Ventilation and perfusion | 763 |
573 | 773 |
Ian G Wilson and Jane E Sellors | 845 |
Endocrinology | 855 |
Mary Doherty and Donal J Buggy | 867 |
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Common terms and phrases
acetylcholine action potential activity agents agonists analgesia analgesic anesthesia Anesthesiology arterial axon barbiturates benzodiazepines binding blood flow brain Ca˛ Ca2+ cardiac output cell cerebral changes Chapter clinical clonidine concentration decrease depolarization desflurane dorsal horn dose drug effects electron enflurane enzyme Equation etomidate excitatory fibers frequency function GABA GABAA receptors gene genetic glutamate halothane increase induction inhalational anesthetics inhibition inhibitory input interactions intracellular intravenous ion channels ischemia isoflurane ketamine kinase mechanisms mediated membrane potential metabolism midazolam modulation molecular molecules monitoring motor muscle Na+ channels nerve terminal neuromuscular neurons neurotransmitter nitrous oxide NMDA receptor nociceptive nociceptors occur opioid pain partial pressure pathways patients peptide peripheral pharmacokinetic phosphorylation plasma postsynaptic presynaptic primary afferent produce propofol protein reduced release respiratory response result sensitization sensory sevoflurane signal solubility specific spinal cord stimulation structures subunit synaptic vesicles target temperature thiopental tissue vapor volatile anesthetics voltage wash-in