Handbook of Pharmaceutical Analysis by HPLC

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Satinder Ahuja, Michael Dong
Elsevier, Feb 9, 2005 - Medical - 600 pages
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High pressure liquid chromatography–frequently called high performance liquid chromatography (HPLC or, LC) is the premier analytical technique in pharmaceutical analysis and is predominantly used in the pharmaceutical industry. Written by selected experts in their respective fields, the Handbook of Pharmaceutical Analysis by HPLC Volume 6, provides a complete yet concise reference guide for utilizing the versatility of HPLC in drug development and quality control. Highlighting novel approaches in HPLC and the latest developments in hyphenated techniques, the book captures the essence of major pharmaceutical applications (assays, stability testing, impurity testing, dissolution testing, cleaning validation, high-throughput screening).

  • A complete reference guide to HPLC
  • Describes best practices in HPLC and offers 'tricks of the trade' in HPLC operation and method development
  • Reviews key HPLC pharmaceutical applications and highlights currents trends in HPLC ancillary techniques, sample preparations, and data handling
 

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Great book for understanding basics of hplc

Contents

Handbook of Pharmaceutical Analysis by HPLC
1
Chapter 2 Key Concepts of HPLC in Pharmaceutical Analysis
19
Status Advances and Trends
47
Chapter 4 HPLC Columns for Pharmaceutical Analysis
77
Chapter 5 Sample Preparation for HPLC Analysis of Drug Products
123
Chapter 6 HPLC Method Development
145
Chapter 7 Validation of HPLC Methods in Pharmaceutical Analysis
191
Chapter 8 Ion Chromatography
219
Chapter 13 Assay and Stability Testing
335
Chapter 14 Impurity Evaluations
359
Chapter 15 HPLC in Dissolution Testing
379
Chapter 16 Cleaning Validation using HPLC for Analysis
401
Chapter 17 LCMS Application in HighThroughput ADME Screen
413
Chapter 18 Chiral Separations
447
Chapter 19 Applications of LCMS in Pharmaceutical Analysis
499
Chapter 20 Application of LCNMR in Pharmaceutical Analysis
569

Practical Aspects in HPLC Operation
255
Chapter 10 Regulatory Considerations in HPLC Analysis
273
Chapter 11 HPLC System Calibration for GMP Compliance
291
Prelnstallation IQ OQ and PQ
303
Its History Advances and Future Direction
581
Chapter 22 New Developments in HPLC
611
Index
631
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Page 48 - Therefore, the goal of this chapter is to provide the reader with a general foundation of the CCITT OSI Model.

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About the author (2005)

Satinder Ahuja earned his PhD in analytical chemistry from the University of the Sciences, Philadelphia. He worked for Novartis Corp. in various leadership positions for over 25 years while simultaneously teaching and guiding research as an adjunct professor at Pace University for over 10 years. As president of Ahuja Consulting, he advises on quality issues relating to chemicals/pharmaceuticals and water. Dr. Ahuja has published numerous papers and more than eighteen books. Two of his latest books are entitled "Water Reclamation and Sustainability" (Elsevier) and Comprehensive "Water Quality and Purification" (Elsevier). Others include "Monitoring Water Quality: Pollution Assessment, Analysis, and Remediation" (Elsevier, 2013); "Novel Solutions to Water Pollution" (ACS Symposium Volume, 2013); "Handbook of Water Purity and Quality" (Elsevier, 2009); and "Arsenic Contamination of Water: Mechanism, Analysis, and Remediation" (Wiley, 2008). A member of the executive committee of Rivers of the World Foundation (ROW), Dr. Ahuja is an expert on improving water quality and has organized numerous global symposia on this topic (American Chemical Society, UNESCO, etc.) In 2013, he gave a lecture on the nexus of food, energy, and water and chaired a symposium on the subject for the American Chemical Society meeting in New Orleans.

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