Handbook of Cannabis
Roger G. Pertwee
Oxford University Press, 2014 - Medical - 747 pages
Truly global in scope and with contributions from leading researchers around the world, The Handbook of Cannabis is the definitive resource on this fascinating drug. Combining scientific perspectives and clinical applications, it covers a vast array of topics, from why over the centuries cannabis has been used as a medicine, through the regulations facing those wishing to self-administer cannabis or provide cannabis-based medicines, to the chemical structure of its many constituents and the rapidly growing group of synthetic cannabinoids that are currently being used for 'legal highs'.
With each chapter written by a group of one or more internationally recognised subject experts, it provides academics and researchers with authoritative scientific material on the main pharmacological actions and their effects, as well as their pharmacokinetics, metabolism, and forensic detection. In addition it also examines the complex morphology, cultivation, harvesting, and processing of cannabis and the ways in which the plant's chemical composition can be controlled.
As well as offering a raft of scientific information there is extensive coverage of cannabinoid-based medicines. Helping readers to identify and evaluate their benefits, chapters explore pharmacological actions and the effects that seem to underlie approved therapeutic uses, how they are currently used to treat certain disorders, and the ever-growing number of wide-ranging potential clinical applications. There is also coverage of both the legal and illegal sources of cannabis, including 'coffee shops' and 'cannabis dispensaries'.
The complex issue of 'recreational cannabis' is also tackled. The sought-after and adverse psychological and non-psychological effects are described and discussions are included on how some adverse effects can be lessened by at least one constituent of cannabis, and that it might be possible to reduce the harm that cannabis does to some by changing current regulatory policies.
The Handbook of Cannabis is a one-stop reference; essential reading for all clinicians, pharmacologists, psychologists, and psychiatrists interested in this drug, as well as those working in the field of public health.
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Part 1 Constituents History International Control Cultivation and Phenotypes of Cannabis
Part 2 Pharmacology Pharmacokinetics Metabolism and Forensics
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acid activity acute Addiction administration anandamide antiemetic antinociceptive associated attenuated behavior brain British Journal cancer cannabichromene cannabidiol cannabigerol cannabinoid CB1 cannabinoid receptor cannabis extract Cannabis sativa cannabis users cation channel CB1 and CB2 CB1 receptor CBDA cells chemotype chronic compounds delta-9-tetrahydrocannabinol diabetic disease disorders doses dronabinol drug effects of cannabinoids effects of cannabis effects of THC efficacy endocannabinoid system function human increased induced inflammation inflammatory inhibition Journal of Pharmacology levels marijuana Mechoulam medical cannabis Medicine metabolism mg/kg mice modulation Molecular mouse multiple sclerosis nabilone nabinoid neurons neuropathic pain neuroprotective Neuroscience oral patients Pertwee Petrocellis Pharmaceutical Pharmacology phytocannabinoids placebo plant plasma potential production Psychiatry psychoactive Psychopharmacology psychosis rats receptor agonist receptor antagonist reduced reported Research response rimonabant role Russo Sativex schizophrenia seizures smoking spasticity symptoms synthetic cannabinoids target tetrahydrocannabinol THCCOOH therapy tion treatment trichomes TRPV1 vitro vivo