Hematology: Clinical Principles and ApplicationsThis comprehensive text examines normal hematopoiesis through diseases of erythroid, myeloid, lymphoid and megakaryocytic origins. Hemostasis and coagulation theory, testing, and instrumentation are also thoroughly discussed. Beautiful full-color illustrations throughout the text enhance comprehension and allow students to realistically visualize hematology concepts. Detailed, full-color illustrations appear near hematology concept discussions to visually support comprehension and recognition.Opening Case Studies present real-life scenarios to apply concepts presented in each chapter.Learning Objectives and Review Questions work together to list expected outcomes and then test those concepts for each chapter.A Bulleted Summary highlights the key concepts at the end of each chapter.Hematology/Hemostasis Reference Ranges inside the front and back covers provide quick reference. Three new chapters detail significant information: An Overview of Clinical Laboratory Hematology, Hematology in Selected Populations, and Monitoring Anticoagulant Therapy.All chapters have been revised to feature the most current technology and research updates.The included Glossary of Terms and consistent pedagogy ensure a cohesive, effective tool for learning.Two well-respected editors contributed more significantly to this third edition: George Fritsma shared his expertise for the Hemostasis section and Kathy Doig managed the pedagogical features. |
Contents
Part I | 1 |
Hematopoiesis | 50 |
Chapter 7 | 57 |
Chapter 9 | 75 |
Metabolism of the Erythrocyte | 94 |
Chapter 10 | 105 |
Chapter 11 | 116 |
Chapter 12 | 124 |
Introduction to Leukocyte Neoplasms | 389 |
Chapter 30 | 398 |
Chapter 31 | 407 |
Chapter 32 | 424 |
Chapter 33 | 451 |
Chapter 34 | 471 |
Myelodysplastic Syndromes | 484 |
Acute Leukemias | 496 |
Chapter 13 | 141 |
Routine Laboratory Evaluation of Blood Cells | 160 |
Examination of the Peripheral Blood Smear and Correlation with the Complete Blood Count | 175 |
Bone Marrow Overview | 193 |
Body Fluid Examination | 205 |
Erythrocyte Disorders | 219 |
Chapter 19 | 232 |
Chapter 20 | 248 |
Bone Marrow Failure | 259 |
Chapter 22 | 271 |
Chapter 23 | 286 |
Chapter 24 | 311 |
Extracorpuscular Defects Leading to Increased Erythrocyte DestructionImmune Causes | 325 |
Hemoglobinopathies Structural Defects in Hemoglobin | 333 |
Thalassemias | 355 |
Leukocyte Disorders | 373 |
Mature Lymphoid Neoplasms | 506 |
Hematology in Selected Populations 541 | 526 |
Cell Counting Automation | 541 |
Hemostasis and Thrombosis | 571 |
Chapter 41 | 588 |
Chapter 42 | 603 |
Chapter 43 | 630 |
Chapter 44 | 654 |
Chapter 45 | 670 |
Chapter 46 | 700 |
Coagulation Instrumentation | 714 |
Appendix Material Safety Data Sheet 729 | 735 |
Glossary | 749 |
| 773 | |
Common terms and phrases
abnormal acid activity acute antibodies antigen aplastic anemia assay basophilic bilirubin binding bleeding blood smear bone marrow cause cell counts cellular Chapter chromosome chronic Clin clinical coagulation cytogenetic cytoplasm decreased detection diagnosis differential disease disorders enzyme erythrocyte erythroid erythropoiesis factor VIII fibrin fibrinogen Figure flow cytometry fluid folate function g/dL gene genetic granules granulocytes Hematol Hematology hematopoietic heme hemoglobin hemolysis hemolytic anemia hemorrhage hemostasis heparin hereditary immunophenotype increased infection intravascular iron deficiency laboratory leukemia leukocyte levels liver lymph lymphocytes lymphoid lymphoma macrocytic macrophages mature megakaryocytes megaloblastic membrane molecular molecule monocytes morphology mutation myelodysplastic syndromes myeloid neutrophils normal nucleated nucleus occurs oxygen pathway patients peripheral blood Philadelphia plasma platelet platelet count precursors present production protein prothrombin receptor reference range reticulocyte count serum sickle cell specimen stain stem cell thalassemia therapy thrombin thrombocytopenia thrombosis tissue transferrin tube vitamin B12 WBC count



