Hematology: Clinical Principles and Applications

Front Cover
Elsevier Health Sciences, Jan 1, 2007 - Medical - 816 pages
This comprehensive text examines normal hematopoiesis through diseases of erythroid, myeloid, lymphoid and megakaryocytic origins. Hemostasis and coagulation theory, testing, and instrumentation are also thoroughly discussed. Beautiful full-color illustrations throughout the text enhance comprehension and allow students to realistically visualize hematology concepts.

Detailed, full-color illustrations appear near hematology concept discussions to visually support comprehension and recognition.Opening Case Studies present real-life scenarios to apply concepts presented in each chapter.Learning Objectives and Review Questions work together to list expected outcomes and then test those concepts for each chapter.A Bulleted Summary highlights the key concepts at the end of each chapter.Hematology/Hemostasis Reference Ranges inside the front and back covers provide quick reference.

Three new chapters detail significant information: An Overview of Clinical Laboratory Hematology, Hematology in Selected Populations, and Monitoring Anticoagulant Therapy.All chapters have been revised to feature the most current technology and research updates.The included Glossary of Terms and consistent pedagogy ensure a cohesive, effective tool for learning.Two well-respected editors contributed more significantly to this third edition: George Fritsma shared his expertise for the Hemostasis section and Kathy Doig managed the pedagogical features.
 

Contents

Part I
1
Hematopoiesis
50
Chapter 7
57
Chapter 9
75
Metabolism of the Erythrocyte
94
Chapter 10
105
Chapter 11
116
Chapter 12
124
Introduction to Leukocyte Neoplasms
389
Chapter 30
398
Chapter 31
407
Chapter 32
424
Chapter 33
451
Chapter 34
471
Myelodysplastic Syndromes
484
Acute Leukemias
496

Chapter 13
141
Routine Laboratory Evaluation of Blood Cells
160
Examination of the Peripheral Blood Smear and Correlation with the Complete Blood Count
175
Bone Marrow Overview
193
Body Fluid Examination
205
Erythrocyte Disorders
219
Chapter 19
232
Chapter 20
248
Bone Marrow Failure
259
Chapter 22
271
Chapter 23
286
Chapter 24
311
Extracorpuscular Defects Leading to Increased Erythrocyte DestructionImmune Causes
325
Hemoglobinopathies Structural Defects in Hemoglobin
333
Thalassemias
355
Leukocyte Disorders
373
Mature Lymphoid Neoplasms
506
Hematology in Selected Populations 541
526
Cell Counting Automation
541
Hemostasis and Thrombosis
571
Chapter 41
588
Chapter 42
603
Chapter 43
630
Chapter 44
654
Chapter 45
670
Chapter 46
700
Coagulation Instrumentation
714
Appendix Material Safety Data Sheet 729
735
Glossary
749
Index
773
Copyright

Common terms and phrases

About the author (2007)

Dr. George Fritsma manages www.fritsmafactor.com, "The Fritsma Factor, Your Interactive Hemostasis Resource," an educational blog supported by Precision BioLogic Inc, Dartmouth, Nova Scotia. Dr. Fritsma also consults for the Laboratory Solutions Program for Developing Nations, supported by BioMedica Diagnostics, Inc., Windsor, Nova Scotia. He is a consultant for the Laboratory Medicine Division of the Pathology Department, University of Alabama at Birmingham School of Medicine, where he provides lectures for pathology residents and for hematology fellows. He is an adjunct Associate Professor for Michigan State and Rutgers University. George chairs the American Association for Clinical Chemistry Press Board and is a consulting editor for the Clinical Laboratory Science journal and is a member of the International Society on Thrombosis and Hemostasis and the International Society for Laboratory Hematology.

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