Human Cytogenetics: Constitutional Analysis : a Practical Approach

Front Cover
Oxford University Press, 2001 - Science - 282 pages
1 Review
Human Cytogenetics: Constitutional Analysis covers all basic aspects of human cytogenetic study other than malignancies and abnormalities. They are covered in a separate volume. Since the publication of the 2nd edition in 1992, there have been major advances in technology and the emphasis of this new edition is on the spectrum of technologies available to conventional and molecular cytogenetics. Perhaps the largest new development has been the transition of fluorescence in situ hybridization to an essential tool for all cytogenetecists and consequently its use in chromosome analysis is covered in detail. Another important new technology to be described in detail is computerised image analysis. The conventional techniques have not been forgotten, with chapters on chromosome staining and banding techniques and meiotic studies. New authors have been brought in to take a fresh look at lymphocyte culture and prenatal diagnosis. As before, there is an introduction to human chromosomes, their analyses, and the application of cytogenetic investigations to clinical practice. There is also an appendix on health and safety concerns in the cytogenetics laboratory. This book will be invaluable to any scientists using basic cytogenetics and along with its sister volume Human Cytogenetics: Malignancy and Acquired Abnormalities will be an essential purchase for any cytogenetics laboratory. The volumes are available individually or as a set.
 

What people are saying - Write a review

User Review - Flag as inappropriate

hello!!! i am a student from AIIMS.
i found this book very helping to me
it made my practical concepts more clear and helped me understand genetics in a better way
i want a e-copy for this book.

Contents

An introduction to human chromosomes and their analysis i
1
Learning to identify chromosomes and their abnormalities
28
Standard lymphocyte culture
34
Urgent samples
42
Special indications for lymphocyte culture
52
The cytogenetics of pregnancy
55
Amniotic fluid
60
Chorionic villi
74
Other banding techniques
121
The application of cytogenetic Investigations to clinical practice
129
Prenatal diagnosis
158
The application of fluorescence in situ hybridization to chromosome
175
Posthybridization washes
190
Troubleshooting
196
Meiotic studies in humans
211
Microscopy and image analysis systems
237

Chromosome staining and banding techniques
99
Constitutive heterochromatin banding
106
Differentia replication staining
114
Al Safety considerations
259
A3 List of suppliers
269
Copyright

Other editions - View all

Common terms and phrases

About the author (2001)

Denise Rooney, NE London Regional Cytogenetics Laboratory.

Bibliographic information