Immunology: A Short Course

Front Cover
John Wiley & Sons, Jan 14, 2009 - Medical - 391 pages
2 Reviews
Immunology: A Short Course, Sixth Edition introduces all the critical topics of modern immunology in clear and succinct yet comprehensive fashion. The authors offer a uniquely balanced coverage of classical and contemporary approaches, basic and clinical aspects. As with the previous editions, the strength of the text is in a complete review of modern immunology without burdening the reader with excessive data or theoretical discussions. Each chapter is divided into short, self-contained units that address key topics illustrated by uniformly drawn, full-color illustrations, many brand new to this edition. The sixth edition of this successful textbook newly covers:
  • Toll-like receptors, their ligands and intracellular activation pathways
  • The key role of activation induced cytidine deaminase (AID) in somatic hypermutation and class switch recombination.
  • The autoimmune regulator (AIRE) gene in self-tolerance and autoimmunity
  • T and B cell activation and the immunological synapse, as well as characterization and mechanisms of action of T regulatory cells


The companion website at www.wiley.com/college/coico features problem sets, quizzes, and a list of relevant internet resources.

Praise for the previous edition:

"This book is clearly a precious resource for undergraduate, graduate and medical students alike… For those who need an introduction to the fascinating world of immunology, this book should most certainly spark the interest."
ANNALS OF BIOMEDICAL ENGINEERING

"… an excellent beginner's guide… the authors have done a terrific job of providing an overview of the field."
YALE JOURNAL OF BIOLOGY AND MEDICINE

 

What people are saying - Write a review

User Review - Flag as inappropriate

One of the big problems with this book is that it jumps a lot from one section to a foward section then backwards. The novice feels at loos as to where he is. Overall though a very good textbook

Contents

Clonal Selection Theory
4
The Short Course Begins Here
10
OVERVIEW OF THE IMMUNE SYSTEM 1 11 CYTOKINES 165
11
Acquired Immunity
19
3
29
Binding of Antigen to AntigenSpecific Antibodies
35
ANTIBODY STRUCTURE AND FUNCTION
41
Immunoglobulin Variants
47
CYTOKINES
165
Cytokine Receptors
174
References
181
FasFasL Interactions
187
Autoimmune Diseases in Which T Cells Play
198
Answers to Review Questions
204
Regulation of Complement Activity
210
Complement Deficiencies
216

Biologic Properties of IgM
53
Review Questions
59
IMMUNOGENS AND ANTIGENS 29 13 COMPLEMENT 205
61
THE GENETIC BASIS OF ANTIBODY
81
Generation of Antibody Diversity
87
7
93
BCell Membrane Proteins
102
17 IMMUNODEFICIENCY DISORDERS
107
Different MHC Molecules Interact with Different Sets
108
BIOLOGY OF THE T LYMPHOCYTE
125
Genes Coding for TCell Receptors
130
References
137
Activation and Function of CD8+ T Cells
153
Summary
244
Contact Sensitivity
249
IMMUNODEFICIENCY DISORDERS
255
Neoplasms of Lymphoid System
273
Summary
280
Immune Mechanisms Responsible for Allograft
287
TUMOR IMMUNOLOGY
299
Limitations of the Effectiveness of Immune Responses
307
ACTIVATION AND FUNCTION TO INFECTIOUS DISEASES
313
Host Defense Against Various Classes of Microbial
315
Active Immunizations
322
Copyright

Other editions - View all

Common terms and phrases

References to this book

About the author (2009)

Dr. Richard Coico is Professor and Chairman of the Department of Microbiology and Immunology and Dean at the City University of New York Medical School. He directs CUNY Microbiology and Immunology courses and also participates directly in the teaching of immunology to graduate students. 

Dr. Sunshine is a Senior Scientist at the Health Effects Institute in Cambridge, Massachusetts. He is also a lecturer in the Department of Pathology at Tufts University School of Medicine.

Bibliographic information