Modular Deficits in Alzheimer-type DementiaBringing models and methods of cognitive neuropsychology to bear on the study of dementing disorders, these contributions present sound evidence that diseases of the Alzheimer type compromise brain function in a highly selective manner, affecting some aspects of cognition while sparing others. Included are original case studies that explore in detail the nature of the linguistic, semantic, and visuoperceptual disorders in patients with degenerative dementias. The book pursues a number of themes with important ramifications for the study of higher mental functions. By exploring the neurocognitive modules that are the targets of degenerative processes, it shows that Alzheimer's disease is not one disease but a complex of disease states, that clinical diversity is an essential feature of Alzheimer's disease and Alzheimer-type dementia, that this diversity reflects to a large extent the differential involvement of particular neural systems that support cognition, and that when suitable methods and models are applied, studies of Alzheimer-type dementia can expand our understanding of basic brain-behavior relations. Myrna F. Schwartz is Director of the Neuropsychology Research Laboratory at Moss Rehabilitation Hospital in Philadelphia. Contributors:M. Moscovitch and C. Umilta, M. F. Schwartz, J. A. Stark, A. R. Damasio, G. W. Van Hoesen, B. T. Hyman, J. B. Chawluk, M. Grossman, J. A. Calcano-Perez, A. Alavi, H. I. Hurtig, M. Reivich, A. Martin, J. Baron, M. Moscovitch, H. Chertkow, D. Bub, E. M. Saffran, E. J. Fitzpatrick-DeSalme, H. B. Coslett. |
Contents
Chapter | 1 |
Clinicopathological Models of Alzheimers Disease and Senile | 61 |
Chapter 3 | 83 |
Chapter 4 | 101 |
Chapter 5 | 143 |
Chapter 6 | 177 |
Chapter 7 | 207 |
Chapter 8 | 245 |
Chapter 9 | 297 |
| 329 | |
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Common terms and phrases
agnosia Alzheimer Alzheimer's disease amnesia analysis Annals of Neurology apraxia Archives of Neurology associated attention behavioral Brain and Language central processes central systems cerebral Chertkow clinical cluster cognitive Cognitive Neuropsychology colleagues control subjects correlations cortex cortical damage Damasio deficits demented difficulty disorder dissociation domain dyslexia effect episodic memory errors evidence example factors focal frontal lobes function glucose hemisphere hippocampus hypometabolism identification procedures identified impairment intact involvement Journal knowledge LCMRgl lesions Martin matching metabolic modular Moscovitch neurofibrillary tangles Neurology neurons neuropathological neuropsychological normal object onset output parietal parietal lobe pathological patients pattern percent perceptual performance Pick's disease picture plaques positron emission tomography probe questions processor progressive aphasia Psychiatry Psychology recognition regions retrieval Saffran Schwartz scores semantic memory senile dementia Shallice spatial specific stimuli structures Susan symptoms target task temporal tion verbal visual field visuoperceptual visuospatial Warrington words