Organogenesis of the KidneyThis description of a model system for cell differentiation and organogenesis is written by one of the foremost researchers in the area. The main emphasis is on the mammalian kidney, but the book also deals with the development of the transien excretory organs. It includes discussions of induction, proliferation, early cytodifferentiation and morphogenesis and organogenesis. This authoritative account will be valuable to developmental biologists and also to scientists working in paediatric nephrology. As it gives the background of normal development and of control systems, it will also be of use to nephrologists working on abnormalities in the urinary tract. |
Contents
1 Ontogenesis of the vertebrate excretory system | 1 |
2 Experimental methods to study kidney development | 35 |
3 Morphogenetic tissue interactions in the kidney | 51 |
4 Experimental tubulogenesis | 88 |
5 Vascularization of the nephron | 129 |
6 Concluding remarks | 143 |
References | 147 |
| 166 | |
| 171 | |
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Common terms and phrases
adhesive aggregates amphibian anlage anlagen antibody avian basement membrane Biol blastema branching capillaries chick chimaeric chymal chyme collagen type collagen type IV components courtesy of Dr Croisille cultivated cytokeratin cytoplasmic detected differentiation distal tubules early condensation Ekblom Electron micrograph electron microscopy embryonic kidney endothelial cells enzyme epithelial cells epithelium experiments explants extracellular matrix fibronectin Fluorescence micrographs glomeruli grafted Grobstein Gruenwald immunohistology incorporation induced mesenchymes inductor intercellular Jokelainen kidney tubule laminin mechanisms mesen mesenchymal cells metanephric mesenchyme metanephrogenic mesenchyme migration model-system monolayer morphogenesis mouse kidney nephric duct nephric mesenchyme nephron observations organogenesis podocytes polarization pore pretubular pronephric proteins proteoglycan proximal tubules quail renal vesicles rudiments S-shaped body Sariola Saxén & Lehtonen spinal cord stage surface synthesis technique Thesleff thymidine tissue interactions transferrin transfilter contact transfilter culture transfilter-induced mesenchymes transplanted tubule formation tubulogenesis uninduced ureter ureteric bud vascular vimentin vitro vivo Wolffian duct