Principles of Medicinal ChemistryWilliam O. Foye, Thomas L. Lemke, David A. Williams This new edition features two new co-authors, extensive revision of the text and current information from the field of medicinal chemistry. It is intended for students of pharmacy. |
Contents
Introduction and History | 1 |
Historical | 7 |
Biopharmaceutical Properties of Drug | 416 |
Copyright | |
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Common terms and phrases
absorption acetylcholine activity administration agents agonist amines amino acid analgesic analogs androgens anesthetic antagonists anti-inflammatory anticonvulsant aromatic Atherosclerosis atoms barbiturates benzodiazepines binding Biochem biologic biosynthesis blood bond carbon cardiac cell CH3 CH3 CH3O Chem chemical cholesterol Clin clinical clofibrate compounds conformation conjugation COOH decrease derivatives diabetes diuretics dopamine dosage dose drug duration of action enzyme ester estrogens excreted factors function gemfibrozil glucocorticoid glucose glucuronide H₁ hepatic hormone human hydrolysis hydroxylation increase inhibition inhibitors insulin interactions ions isomer levels lipid liver lovastatin mechanism membrane metabolism metabolites methyl molecular molecule morphine muscarinic muscle neurons nicotinic norepinephrine OCH3 opioid oral oxidation patients peptide Pharmacol pharmacologic phenylbutazone phenytoin plasma potent probucol produce protein reactions receptor reduced release result ring salicylates seizures side chain side effects sodium solubility steroid stimulation structure substituted substrate sulfonylureas synthesis Table therapeutic therapy tion tissue toxicity treatment urine xenobiotics