Principles of Regenerative BiologyBruce M. Carlson With the explosion of knowledge from molecular biology and the burgeoning interest in generating or regenerating tissues or organs through various bioengineering or stem cell approaches, many scientists and students have shown a renewed interest in the phenomenon of regeneration. Because relatively few have had the luxury of being able to approach the phenomenon of regeneration from a broad biological perspective, Dr. Carlson has produced a book that outlines the fundamental principles of regeneration biology. Subject matters focus principally on regeneration in vertebrate systems, but also invertebrate regeneration. In order to manipulate regenerative processes, it is important to understand the underlying principles of regeneration. Principles of Regnerative Biology is the key introductory reference for all developmental biologists, geneticists, and tissue and stem cell researchers.
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Contents
| 1 | |
| 31 | |
| 49 | |
Role of the Substrate in Regeneration | 73 |
Tissue Interactions in Regeneration | 93 |
Role of the Nerve in Regeneration | 111 |
Morphogenesis of Regenerating Structures | 127 |
Reintegrative Processes in Regeneration | 165 |
Regeneration and Aging | 205 |
Influence of the Environment on Mammalian Regeneration | 221 |
Stem Cells Plasticity and Regeneration | 239 |
Tissue Engineering and Regeneration | 259 |
Stimulation of Regeneration | 279 |
What Have We Learned and Where Are We Going? | 305 |
REFERENCES | 325 |
Index | 371 |
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Common terms and phrases
activity adult amphibian amphibian limb amputation amputation surface angiogenesis antler axons basal lamina blastema bone buds Carlson cartilage cellular collagen components cytokines damaged denervated differentiation distal dorsal iris early embryonic endothelial cells environment epidermal cells epimorphic regeneration epithelial cells epithelium experimental experiments extracellular matrix fibroblasts fibronectin formation fracture functional genes grafted growth factor host implanted important induced inhibit inhibitors innervation interactions involves limb regeneration limb stump liver macrophages mammalian mammals mechanical migration minced muscle mitosis mitotic molecular molecules morphogenesis morphogenetic muscle fibers muscle regeneration myelin myoblasts myotubes neural neurons newt normal occurs organs peripheral nerve planaria progenitor cells proliferation protein proximodistal receptor regenerating limb regeneration blastema regenerative process retina role satellite cells scar Schwann cells segments skeletal muscle skin wounds spinal cord stem cells stem-cell stimulate structure substrate tail tion tissue engineering tissue regeneration transplantation types underlying urodele vascular wound epidermis wound healing
Popular passages
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Page 364 - Terada N, Hamazaki T, Oka M, Hoki M, Mastalerz DM, Nakano Y, Meyer EM, Morel L, Petersen BE, Scott EW: Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion.
Page 330 - Iten. 1976. Supernumerary limbs in amphibians: Experimental production in Notophthalmus viridescens and a new interpretation of their formation. Dev Biol 50:212-234.
Page 345 - Kopen GC, Prockop DJ, Phinney DG. Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains. Proc Natl Acad Sci USA 1999; 96:10711-10716.
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Page 345 - Korbling M, Katz RL, Khanna A et al. Hepatocytes and epithelial cells of donor origin in recipients of peripheral-blood stem cells. N Engl J Med 2002;346:738-46.