Quality of Life: The Assessment, Analysis and Interpretation of Patient-reported OutcomesQuality of life studies form an essential part of the evaluation of any treatment. Written by two authors who are well respected within this field, Quality of Life: The Assessment, Analysis and Interpretation of Patient-reported Outcomes, Second Edition lays down guidelines on assessing, analysing and interpreting quality of life data. The new edition of this standard book has been completely revised, updated and expanded to reflect many methodological developments emerged since the publication of the first edition.
This book is of interest for everyone involved in quality of life research, and it is applicable to medical and non-medical, statistical and non-statistical readers. It is of particular relevance for clinical and biomedical researchers within both the pharmaceutical industry and practitioners in the fields of cancer and other chronic diseases. Reviews of the First Edition – Winner of the first prize in the Basis of Medicine Category of the BMA Medical Book Competition 2001: “This book is highly recommended to clinicians who are actively involved in the planning, analysis and publication of QoL research.” CLINICAL ONCOLOGY “This book is highly recommended reading.” QUALITY OF LIFE RESEARCH |
Contents
Introduction | 1 |
Principles of measurement scales | |
Developing a questionnaire | |
validity reliability sensitivity | |
Multiitem scales | |
Factor analysis and structural equation modelling | |
Item response theory and differential item functioning | |
Item banks item linking and computeradaptive tests | |
Modelling longitudinal data | |
Missing data | |
Practical and reporting issues | |
ualit adusted survival | |
Clinical interpretation | |
Metaanalysis | |
Generic instruments | |
Diseasespecific instruments | |
Choosing and scoring questionnaires | |
Clinical trials | |
Sample sizes | |
Crosssectional analysis | |
Exploring longitudinal data | |
E10 ualit of Life in E lie 5 OLIE89 Extract | |
ADL and disability | |
References | |
Other editions - View all
Quality of Life: The Assessment, Analysis and Interpretation of Patient ... Peter Fayers,David Machin No preview available - 2007 |
Quality of Life: The Assessment, Analysis and Interpretation of Patient ... Peter Fayers,David Machin No preview available - 2007 |
Common terms and phrases
ANOVA anxiety applied auto-correlation baseline bias Bjordal calculated cancer patients causal variables Chapter chemotherapy clinical trials coefficient comparing complete compliance Computer-adaptive testing construct validity correlation corresponding Cronbach’s depression described difficulty disease effect size endpoint EORTC QLQ-C30 equation estimate evaluation example factor analysis fatigue Figure groups of patients important imputation IRT models issues item response theory latent variable levels literature logistic logistic regression lung cancer mean measure Medical meta-analysis methods missing data multi-item scales multiple multiple myeloma Normal distribution number of patients observed ordered categorical outcomes overall QoL p-value pain physical functioning plot population problems proportion psychometric QoL assessment QoL data QoL instruments QoL questionnaires QoL scales QoL scores quality-adjusted random random-effects model randomised range Rasch model regression relevant reliability reported Research sample scale score sensitivity specific statistically significant summary symptoms Table therapy treatment effect treatment groups