The Chemistry of Heterocyclic Compounds, Thiazole and Its Derivatives
Jacques V. Metzger
John Wiley & Sons, Sep 15, 2009 - Science - 612 pages
The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.
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2-aminothiazole 2-position 4-Methyl 4-methylthiazole Absln Absm Absrn Absrr Abstn Abstr Acad acetic Acetone Acta alcohol reﬂux alkyl alkylthiazoles Amer aminothiazoles aryl aryl group atom benzene Berichte British Patent Bull carbon carboxylic Chem chemical shifts Chim chloride CHZCI CHZCOZH CHzPh compounds condensation conﬁrmed corresponding COZEt cyclization dioxane Erlenmeyer esters ether ﬁrst France German Patent H A(Br H A(Cl H Cl H Me H H Ph H. J. M. Dou Hantzsch heat Helv heterocyclic hydrogen Indian Chem isothiazole Japanese Patent Justus Liebigs Justus Liebigs Ann ketones Khim method methyl Metzger n-Pr nitrogen nucleophilic Obshchei Khim obtained Ph H Pharm phenyl position prepared proton pyridine react reaction reactivity reﬂux 5 hr rhodaninic Scheme solvent substituent sulfur synthesis TABLE Tcherniac Tetrahedron thiazole thiazole derivatives thiazole ring thiazolium salts thioamides thiophene thiourea U.S. Patent University of Marseille Vernin vibrations yield