Vitamin C in Health and Disease"Provides an up-to-the-minute, comprehensive analysis of the most recent theoretical and clinical developments in vitamin C research--integrating a wide variety of interdisciplinary studies into a single-source volume. Highlights the redox properties of vitamin C, including regeneration, participation in antioxidant networks, and influence on atherosclerosis." |
Contents
A History of Scurvy and Vitamin C | 1 |
CHEMISTRY AND BIOCHEMISTRY | 23 |
Antioxidant and Prooxidant Properties of Vitamin C | 59 |
The Vitamin C Radical and Its Reactions | 75 |
Vitamin C and Redox Cycling Antioxidants | 95 |
Regeneration of Vitamin C | 109 |
Protein Glycation by the Oxidation Products of Ascorbic Acid | 123 |
Ascorbate Membrane Transport Properties | 143 |
Effect of Vitamin C on Leukocyte Function and Adhesion | 295 |
Mechanisms Underlying the Action of Vitamin C in Viral | 309 |
Blood Vitamin C in Human Glucose6Phosphate Dehydrogenase | 323 |
Vitamin C in Cutaneous Biology | 333 |
Human Metabolism and the Requirement for Vitamin C | 341 |
Vitamin C Safety in Humans | 367 |
Vitamin C in Prospective Epidemiological Studies | 381 |
Nitrogen Oxides Are Important Contributors to Cigarette SmokeInduced | 399 |
Mechanisms of Action | 163 |
Protection of Human LowDensity Lipoprotein from Oxidative | 183 |
The Importance of Ascorbate as | 193 |
Vitamin C Collagen Biosynthesis and Aging | 205 |
Oxidative Stress and Ascorbate in Relation to Risk for Cataract | 231 |
Antioxidant Action of Vitamin C in the Lung | 265 |
Vitamin C and Asthma | 279 |
Common terms and phrases
a-tocopherol Acad Sci USA activity alcohol Ann NY Acad antioxidant ascorbic acid associated asthma atherosclerosis Biochem Biophys Biol Chem blood cancer cataract cells cellular cigarette smoke Clin Nutr 1991 clinical collagen common cold concentrations decreased deficiency dehydroascorbic acid DHAA diabetes diet doses effect of ascorbic effect of vitamin enzyme extracellular factors formation free radical function g/day glutathione glycation guinea pigs Health human hydroxylation increased infections inhibition intake of vitamin interaction L-ascorbic lens leukocytes lipid peroxidation low density lipoprotein low-density lipoprotein lung mechanism membrane metabolism mg/d Natl Acad Sci neutrophils nonsmokers Nutrient Nutrition Ophthalmol oxidative damage oxidative stress oxygen patients periodontal disease plasma ascorbic plasma vitamin Proc Natl Acad prooxidant protection protein reactions reactive redox reduced reductase risk role scurvy serum skin studies superoxide tissue vitamin C intake vitamin C status vitamin C supplementation vitamin E vitro vivo