What is Life?: How Chemistry Becomes Biology

Front Cover
OUP Oxford, Sep 27, 2012 - Science - 200 pages
In his famous 1944 text What is Life? Erwin Schrodinger pointed out how strange living systems appeared to be when viewed from a strictly physical standpoint. All living systems are highly organized and the emergence of these organized systems would seem to contradict the most basic tenets of physics and chemistry, which say that systems tend toward chaos and disorder. What is even more remarkable is that despite dramatic developments in molecular biology in the half century since Schroedinger's remarks, we still don't understand what life is or how it relates to the inanimate world. In addressing Schrodinger's classic question, the author offers a radically new approach to these fundamental questions of biology, what is life and how did it emerge. He examines these issues from a chemical perspective, providing a new understanding of how the sciences of chemistry and biology relate to one another. He shows that recent developments in a new area of chemistry called "systems chemistry" now allow researchers to outline the chemistry-biology connection, shedding light on how and why some prebiotic chemical systems are able to make the magical transformation from inanimate to animate. Through the application of these simple chemical concepts, this book reveals the essence of the animate-inanimate connection, explains the strange properties of living systems in chemical terms, and offers profound new insights into classical biological issues, such the mechanism and driving force for evolution and the origin of altruism. Here the author reveals that the emergence of life on Earth and classical Darwinian theory are intimately related; that Darwinian theory is just the biological expression of a more general chemical principle, one that Darwin himself predicted would likely be uncovered in time. -- From publisher's description.
 

Contents

1 Living Things are so Very Strange
1
2 The Quest for a Theory of Life
32
3 Understanding Understanding
43
4 Stability and Instability
58
5 The Knotty Origin of Life Problem
82
6 Biologys Crisis of Identity
111
7 Biology is Chemistry
122
8 What is Life?
160
References and Notes
193
Index
199
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About the author (2012)

Addy Pross received a Ph.D in Organic Chemistry from Sydney University in 1970. He is currently a Professor of Chemistry at Ben Gurion University of the Negev, Israel, and a recognized authority in the area of chemical reactivity to which he contributed with the highly cited and acclaimed Pross-Shaik model of chemical reactivity. He has held visiting positions in many universities word-wide, including the University of Lund, Stanford University, Rutgers University, University of California at Irvine, University of Padova, the Australian National University Canberra, and Sydney University. He has served on the editorial board of chemical and biological journals and a variety of academic management boards. In recent years he has directed his attention to the biological arena where he has applied his expertise in chemical reactivity to the Origin of Life problem and the broader question of the problematic chemistry-biology interface.

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