Wilson and Gisvold's Textbook of Organic Medicinal and Pharmaceutical ChemistryReflecting the breakthroughs since the first edition, this tenth edition examines pharmacotherapeutics, and includes new chapters on drug latentiation and prodrugs, immunizing biologicals, diagnostic imaging agents, and biotechnology. All chapters from the previous edition have been revised to incorporate material on new drugs and advances in understanding how drugs act on biological systems. |
Contents
CHAPTER | 1 |
AcidBase Properties | 10 |
Statistical Prediction of Pharmacological Activity | 18 |
Copyright | |
86 other sections not shown
Common terms and phrases
acetylators acid activity administration agents alcohol alkylating amines amino aminoglycosides ampicillin antibacterial antibiotics antibody antigenic antimalarial Antimicrob aromatic atom B-lactam B-lactamases bacteria bacterial binding Biochem biological cancer carbenicillin cell cephalosporins CH₂ CH3 CH3 Chem chemical Clin clinical cloned compounds conjugate COOH crystalline cytochrome derivatives disease dose drug metabolism effective enzymes erythromycin ester excreted function gastrointestinal gene gentamicin gram-negative gram-positive half-life hepatic human hydrochloride hydrolysis hydroxylation immune inactivation infections caused inhibit inhibitor intravenous isoniazid kanamycin liver malaria membrane Metab metabolite moiety molecule occurs oral organic oxidation parenteral patients penicillin Pharm Pharmacol phenol plasma potential prodrug produced properties protein quinolones reactions receptor recombinant resistant ring salt semisynthetic sodium soluble in water solution species strains streptomycin structure substituents sulfate sulfonamides synthesis tetracyclines Ther therapy tion tissue toxicity tract treatment trimethoprim tumor undergo urinary urine vaccine viral water-soluble