with the lint covering the fungus, and this seems to have checked its rapid growth. Death took place May 19, 1858. The late Dr. Knox's notes at the post-mortem examination."The head presented a very shocking spectacle. The fungus covered all the forehead, vertex, and sides of the head, and hung down in masses over the eyes and nose. On raising these up, the nostrils were found to be so compressed as evidently to have interrupted all breathing through the nose. The right eye appeared to have sunk altogether into the orbit, but the disease did not involve the integuments of the nose nor the eyelids, and seemed limited in this direction to the forehead. In attempting to remove some of the mass from the forehead, a very large abscess was opened. The disease having been taken away, and the frontal bone exposed to view, a portion of it was removed, extending from the frontal sinuses upwards to the vertex, the pericranium over the lower portion of the bone was diseased, partaking somewhat of the cancerous character, and a perforation was discovered the size of a goose-quill; through this perforation the disease penetrated into the interior, communicating with a small diseased mass involving to some extent the dura mater. In other respects the bone seemed healthy, and was merely thinned away around the margins of the opening, but nothing like caries appeared anywhere. Turning now to the interior or cerebral aspect of the osseous portion, we find that the dura mater, perfectly sound in the upper part, becomes gradually diseased on approaching the lower portion in the vicinity of the aperture, the bone being more and more vascular, but not much thickened, if at all. On its outer surface there lay small masses of diseased structure, whilst internally similar small masses were found apparently embedded in its substance, and adhering to the surface of the brain, which they had involved to the extent of a filbert. On dividing the largest of the tumours, thus seemingly originating in the dura mater, its identity with those on the exterior of the cranium became evident, and the nature of the disease was no longer to be questioned. Thus was confirmed the original diagnosis of Dr. Marsden that the disease originated in the interior of the head. One only of the tumours had perforated the bone and thus gained the surface of the body. A similar tumour occupied the right frontal sinus; this seemed also to have made its way from the interior near the upper part of the sinus, the lining membrane of which, as well as the osseous structure, was sound, the left sinus presenting similar appearances. In both was found a bright yellow substance, the brightness of whose colours attracted the attention of the attendants during the dissection." FORMULE. The following formulæ will be found useful in the treatment of Cancer. Ꭱ Acid. Phosphor. dil. āā m xv. To be taken twice or three times a day. No. 2. Spiritus Chloroformi, m 40 vel 60. To be taken in a wineglass of water twice or three times a day. R No. 3. Acid. Hydrochlor. dil. Aquæ ad. 3 viij. Misce. Two tablespoonfuls to be taken twice or three times a day. Ꭱ No. 4. Quinæ Sulph. Aquæ, 3j. Misce. To be taken twice or three times a day. The above are all good tonics in cancer. The first and fourth are specially useful when there is much cachexia, and the second when it is desirable to combine a stimulant with a tonic. Acidi Citrici. Potassæ Bicarb. āā 3 ij. Tinct. Aurantii, 3 vj. Aquæ, ad. 3 viij. Misce. Two tablespoonfuls to be taken every three or four hours. An excellent saline, and to allay sickness. Soda Bicarbonatis, 3ss. Aquæ Ferventis, Oj. Macerate for four hours, and strain. Dose, two or three tablespoonfuls twice or thrice a day. An excellent stomachic. Pulv. Rhei, gr. 45. Soda Bicarb. 3 ss. Divide into 14 powders, one to be taken in a wineglass of water twice a day. Stomachic. After either of the above have been taken for a week or ten days, a patient who could not previously bear tonics will often do so. Magnes. Sulph. iss. Pulv. Rhei, gr. xx. Divide into 14 powders. One to be taken every morning, or twice a day, in a wineglass of water. A gentle saline aperient. It acts more on the bowels if taken fasting early in the morning and in half a tumbler of warm water. If a stronger dose is required it may be divided into seven powders only. B No. 10. Morphiæ Hydrochlor. gr. ij. Divide into four or six pills-one to be taken at bed time, or at any time when pain is severe. R No. 11. Boracis, 3 ss. Aquæ, ad. Ojss. Misce. Make into a lotion. Made also without the glycerine. The above are excellent lotions; or gargles in Cancer of the Tongue, Fauces, or Throat. Make a lotion or injection. Made also with 3j. of Tinct. Opii. The acid to be poured directly on the Chlorate of Potash, and the water added gradually. To be used as a lotion or injection. R No. 17. Potassæ Permang, gr. 40 Make a lotion or injection. The above lotions are all useful in cancerous ulceration of the breast or other part of the body, and as injections in cancerous ulceration of the uterus. Nos. 13, 16, and 17, check offensive smell. No. 14 arrests, and allays pain both before and after, ulceration. No. 15 is useful when there is a tendency to hæmorrhage, and may be used of any strength; the pure tincture being applied when bleeding is actually taking place. No. 18. B Liquor Arsenicalis, 3 ss. vel 3j. Make a lotion. Useful in lupus and some forms of cancer. |