Nature, Volume 429Sir Norman Lockyer Macmillan Journals Limited, 2004 - Electronic journals |
From inside the book
Results 1-3 of 5
Page 311
... RN - tre . RN - tre exerted a strong inhibition on circular ruffles ( Figs la and 2a ) . A catalytic mutant ( RN - treR150 ) displays no GAP activity on Rab5 , and is inactive in bioassays in which wild - type RN - tre can suppress ...
... RN - tre . RN - tre exerted a strong inhibition on circular ruffles ( Figs la and 2a ) . A catalytic mutant ( RN - treR150 ) displays no GAP activity on Rab5 , and is inactive in bioassays in which wild - type RN - tre can suppress ...
Page 312
... RN - tre mutants to inhibit circular ruffling perfectly correlated with their ability to inhibit macropinocytosis ( Fig . 2b ) . Thus , two indepen- dent molecular functions of the RN - tre protein ( that is , the GAP activity and ...
... RN - tre mutants to inhibit circular ruffling perfectly correlated with their ability to inhibit macropinocytosis ( Fig . 2b ) . Thus , two indepen- dent molecular functions of the RN - tre protein ( that is , the GAP activity and ...
Page 313
... RN - tre and Rab5 . A simple possibility to explain the connections among these three proteins is to postulate that RN - tre is an effector of Rab5 . GAP proteins bind preferentially to the GTP- bound forms of small GTPases , thus ...
... RN - tre and Rab5 . A simple possibility to explain the connections among these three proteins is to postulate that RN - tre is an effector of Rab5 . GAP proteins bind preferentially to the GTP- bound forms of small GTPases , thus ...
Other editions - View all
Common terms and phrases
acid activity analysis antibodies apoptosis applications AQPO assays asteroids B-cells bioinformatics Biol biotechnology cancer candidates caspase cell biology cellular Centre climate clinical cloning COP1 core culture Department detection disease domain drug e-mail effects experience expression field function funding galectin-2 gastrulation gene genetic genome global granule cells growth human increase indicate Institute interactions Japan laboratory ligand magnetic mammalian MDMA mechanism membrane mice molecular biology molecules mouse mutant nature publishing group Naturejobs neurons Neuroscience nuclear observed ocean ORF2 oxygen photons Phys pollen pollen tubes position postdoctoral potential predicted production protein proteomics publishing group npg Rap1 rats receptor region response retrotransposition retrotransposon ribozyme RN-tre says Science scientific scientists sequence signal siRNA species stem cells structure Supplementary Fig surface target temperature tissue transcription transfected transgenic University wild-type