Nature, Volume 429Sir Norman Lockyer Macmillan Journals Limited, 2004 - Electronic journals |
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Page 433
... mutant has the mutations Arg117Ala , Arg144Ala and Asn201Ala . The aromatic patch mutant contains Trp91Gly , Trp98Gly , Trp100Gly and Try102Ala substitutions in CdtA . The deletion mutant ( CdtC A21–35 ) was generated by PCR and cloned ...
... mutant has the mutations Arg117Ala , Arg144Ala and Asn201Ala . The aromatic patch mutant contains Trp91Gly , Trp98Gly , Trp100Gly and Try102Ala substitutions in CdtA . The deletion mutant ( CdtC A21–35 ) was generated by PCR and cloned ...
Page 897
... mutation . We have previously shown that duplication of the mutant neo gene at this locus , which represents ' bi - allelic mutation ' , can be selected by high doses of G418 ( ref . 11 ) . The rate of the duplication determined by ...
... mutation . We have previously shown that duplication of the mutant neo gene at this locus , which represents ' bi - allelic mutation ' , can be selected by high doses of G418 ( ref . 11 ) . The rate of the duplication determined by ...
Page 898
... mutation , their mutants were probably derived from single clones . Therefore , the difference in mutant numbers would be explained by the differences in the stages at which the mutants were generated after the addition of dox ...
... mutation , their mutants were probably derived from single clones . Therefore , the difference in mutant numbers would be explained by the differences in the stages at which the mutants were generated after the addition of dox ...
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