Phytotherapies: Efficacy, Safety, and RegulationIqbal Ramzan Covering fundamentals and new developments in phytotherapy, this book combines pharmaceutical sciences and chemistry with clinical issues. • Helps readers better understand phytotherapy and learn the fundamentals of and how to analyze phytotherapeutic agents • Discusses phytotherapy in modern medicine, chemoprevention of disease, and alternatives to western medicines for specific diseases • Chapters summarizes the uses and applications of phytomedicines, by type like Chinese, Greco-Arab, Indian, European, and Ayurvedic • Includes international regulatory perspectives and discusses emerging regulations for various established and emerging markets |
Contents
1 | |
Key Considerations Methods and Analytical Challenges | 18 |
Chapter 3 Preclinical In Vivo and Laboratory In Vitro Evidence of Phytomedicine Efficacy | 49 |
Chapter 4 Clinical Efficacy Trials with Natural Products and Herbal Medicines | 65 |
Chapter 5 Novel Formulations and Drug Delivery Systems for Phytotherapies | 89 |
Chapter 6 Phytotherapies Used by Indigenous Populations | 101 |
Chapter 7 Phytotherapies from Traditional Chinese Medicine | 122 |
Chapter 8 Integrating Traditional GrecoArab and Islamic Diet and Herbal Medicines in Research and Clinical Practice | 142 |
Chapter 15 Phytotherapies for the Management of Obesity and Diabetes | 370 |
Chapter 16 Phytotherapeutics for Cancer Therapy | 394 |
Chapter 17 Phytomedicines for Fatty Liver Disease and Functional Gastrointestinal Conditions | 429 |
Chapter 18 Phytomedicines for Inflammatory Conditions | 464 |
Are These Really Useful? | 483 |
Safety Issues for Use with Antiepileptic Drugs | 504 |
Drug Interactions in Cancer | 536 |
Considerations in Phytotherapy | 554 |
Chapter 9 Evolution of Herbal Medicines in Europe and Its Relationship with Modern Medicine | 183 |
Chapter 10 Chemical Classification and Chemistry of Phytotherapeutics Constituents | 199 |
Chapter 11 Therapeutic Potential of Ginsenosides in Management of Atherosclerosis | 236 |
Chapter 12 Phytotherapy Pharmacophores for Major Cellular Drug Targets | 268 |
Chapter 13 Use of Kava as a Phytotherapeutic Agent and KavaRelated Hepatotoxicity | 312 |
Gossypol and Curcumin | 330 |
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activity agents alkaloids alternative medicine analogues anti‐inflammatory anticancer antioxidant apoptosis atherosclerosis Australia biological catechins chemical chemotherapy Chen Clin clinical trials complementary medicines compounds constituents cranberry curcumin cytotoxicity decreased diabetes dietary supplements disease dose drug effects efficacy EGCG endothelial enzymes evaluation extract fatty acids flavonoids Food ginseng Ginsenoside glucose gossypol green tea hepatic hepatotoxicity herbal medicinal products herbs human increase induced infections/slow healing wounds inflammation ingredients inhibition inhibitors interactions Journal kava lentinan Linn lipid liver medicinal plants metabolism mice natural products Nigella sativa notoginseng oral oxidative Panax patients Pharm pharmaceutical pharmacokinetics Pharmacol pharmacological pharmacophore pharmacophore model phenytoin phytomedicines phytotherapeutic phytotherapies placebo polyphenols Polyphenon E potential properties protein Radix rats receptor regulations reported resveratrol Rhizoma safety saponins silymarin Skin infections/slow healing species therapeutic therapy toxicity traditional Chinese medicine traditional medicine treatment vitro vivo Wang Zhang