Immunology: A Short CourseImmunology: A Short Course, 7th Edition introduces all the critical topics of modern immunology in a clear and succinct yet comprehensive fashion. The authors offer uniquely-balanced coverage of classical and contemporary approaches and basic and clinical aspects. The strength of Immunology: A Short Course is in providing a complete review of modern immunology without the burden of excessive data or theoretical discussions. Each chapter is divided into short, self-contained units that address key topics, illustrated by uniformly drawn, full-color illustrations and photographs. This new edition of Immunology: A Short Course: • Has been fully revised and updated, with a brand new art program to help reinforce learning • Includes a new chapter on Innate Immunity to reflect the growth in knowledge in this area • Highlights important therapeutic successes resulting from targeted antibody therapies • Includes end of chapter summaries and review questions, a companion website at www.wileyimmunology.com/coico featuring interactive flashcards, USMLE-style interactive MCQs, figures as PowerPoint slides, and case-based material to help understand clinical applications |
Contents
Chapter 1 Overview of the Immune System | 1 |
Chapter 2 Innate Immunity | 11 |
Chapter 3 Adaptive Immunity | 26 |
Chapter 4 Immunogens and Antigens | 35 |
Chapter 5 Antibody Structure and Function | 47 |
Chapter 6 AntigenAntibody Interactions Immune Assays and Experimental Systems | 67 |
Chapter 7 The Genetic Basis of Antibody Structure | 88 |
Chapter 8 Biology of the B Lymphocyte | 100 |
Chapter 14 Complement | 217 |
Type I | 233 |
Types II and III | 249 |
Type IV | 259 |
Chapter 18 Immunodeficiency Disorders and Neoplasias of the Lymphoid System | 268 |
Chapter 19 Transplantation | 298 |
Chapter 20 Tumor Immunology | 312 |
Chapter 21 Resistance and Immunization to Infectious Diseases | 328 |
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Common terms and phrases
adaptive immune anti antibody antigen antigen-specific APCs apoptosis associated autoimmune disease bacteria binding blood bone marrow CD4+ T cells CD8+ cell surface cells expressing cellular Chapter chemokine class I molecules class switch clinical co-stimulator components cytokines cytotoxic deficiency dendritic cells differentiation ecules effector enzymes epitope factor Figure function germinal center H-chain host cells human hypersensitivity immune complexes immune response immune system immunodeficiency immunogenic immunoglobulin Immunol Immunology individual induce infection inflammatory innate immune interaction involved isotype leukocytes lymph nodes lymphocytes lymphoma macrophages mast cells mechanisms mediated membrane MHC class MHC class II MHC molecules mice molecular molecules monoclonal mutation neutrophils NK cells normal pathogens pathway patients peptides phagocytic plasma cells produced protein reactions rearrangement receptor region result role self-antigen serum signal specific subsets syndrome synthesized therapy thymus tion tissue transplantation Treg tumor cells vaccine viral virus viruses