Nature, Volume 450Sir Norman Lockyer Macmillan Journals Limited, 2007 - Science |
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Page 255
... cytoplasmic tails within a dimer are separated from each other but HH signalling increases their proximity . To investigate whether increased proximity is accompanied by a conformational change , we generated a doubly tagged SMO ( SMO ...
... cytoplasmic tails within a dimer are separated from each other but HH signalling increases their proximity . To investigate whether increased proximity is accompanied by a conformational change , we generated a doubly tagged SMO ( SMO ...
Page 256
... cytoplasmic tails in a closed inactive conformation that prevents their association . Consistent with this model , FRET between EB2- SMOCSA CFPC / EB2 - SMOCSA - YFPC remained low after EphB2 - Fc treatment ( Fig . 5d ) . EphB2 - Fc ...
... cytoplasmic tails in a closed inactive conformation that prevents their association . Consistent with this model , FRET between EB2- SMOCSA CFPC / EB2 - SMOCSA - YFPC remained low after EphB2 - Fc treatment ( Fig . 5d ) . EphB2 - Fc ...
Page 696
... cytoplasmic outer ring . They add significant extra mass to the cytoplasmic side of the NPC compared with the nucleoplasmic side , probably accounting for much of the extra density of the cytoplasmic ring seen by electron microscopy ...
... cytoplasmic outer ring . They add significant extra mass to the cytoplasmic side of the NPC compared with the nucleoplasmic side , probably accounting for much of the extra density of the cytoplasmic ring seen by electron microscopy ...
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