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activity addition allow analysis applications approach associated atoms authors behaviour Biol Biology brain candidates carbon cells Center changes compared complex conservation cytoplasmic Department dependence disease Drosophila effect elements energy et al evolution example experience expression factor field Figure function further future genes genetic genome human imaging increased indicated Institute interactions interest laboratory leading levels mean measured mechanisms Medical melanogaster methods mice Michigan molecular motifs mutant Nature neurons November observed organ position predicted present protein Publishing receptor reference region regulation response role says Science scientific scientists selection sequence shown signal similar single species structure studies suggesting Supplementary Fig Technology transcription University