Nature, Volume 450Sir Norman Lockyer Macmillan Journals Limited, 2007 - Science |
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Page 359
... histone modification , nethylation is the most stable . For example , precise patterns of trimethylated lysine residues at positions 9 or 27 of the amino - acid sequence of histone H3 can be maintained through many cell cycles in ...
... histone modification , nethylation is the most stable . For example , precise patterns of trimethylated lysine residues at positions 9 or 27 of the amino - acid sequence of histone H3 can be maintained through many cell cycles in ...
Page 440
... histone H3 containing a tri- methyl group at its lysine 9 position ( H3K9me3 ) in regions of heterochromatin2 . SIRT1 is an NAD * -dependent deacetylase that targets histone H4 at lysine 16 ( refs 3 and 4 ) , and through an un- known ...
... histone H3 containing a tri- methyl group at its lysine 9 position ( H3K9me3 ) in regions of heterochromatin2 . SIRT1 is an NAD * -dependent deacetylase that targets histone H4 at lysine 16 ( refs 3 and 4 ) , and through an un- known ...
Page 444
... histone modifications during the formation of heterochromatin . This underscores that the enzymes responsible for pivotal histone modifications do not function in isolation , but are co - regulatory . SIRT1 exhibits a multi - pronged ...
... histone modifications during the formation of heterochromatin . This underscores that the enzymes responsible for pivotal histone modifications do not function in isolation , but are co - regulatory . SIRT1 exhibits a multi - pronged ...
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