Clinical and Statistical Considerations in Personalized MedicineClaudio Carini, Sandeep M Menon, Mark Chang Clinical and Statistical Considerations in Personalized Medicine explores recent advances related to biomarkers and their translation into clinical development. Leading clinicians, biostatisticians, regulators, commercial professionals, and researchers address the opportunities and challenges in successfully applying biomarkers in drug discovery and preclinical and clinical development. Robust Biomarkers for Drug Development and Disease Treatment Improve Patient Care and Reduce Costs and Side Effects |
Contents
1 | |
RNAi Screens Triumphs and Tribulations | 27 |
Current Advances in Epigenetics | 75 |
Biomarkers and Precision Medicine The Case of Rare Diseases | 117 |
BiomarkerInformed Adaptive Design | 129 |
Fitting the Dose Adaptive Staggered Dose Design | 149 |
EvidenceBased Adaptive Statistical Decision and Design Strategies for | 179 |
Biomarker Identification in Clinical Trials | 211 |
Multiplicity in Pharmacogenomics | 265 |
PatientReported Outcomes in Personalized Medicine | 297 |
Regulatory Issues in Use of Biomarkers in Drug Development | 313 |
Back Cover | 349 |
Other editions - View all
Clinical and Statistical Considerations in Personalized Medicine Claudio Carini,Sandeep M. Menon,Mark Chang No preview available - 2019 |
Clinical and Statistical Considerations in Personalized Medicine Claudio Carini,Sandeep M Menon,Mark Chang No preview available - 2014 |
Clinical and Statistical Considerations in Personalized Medicine Claudio Carini No preview available - 2014 |