Nature, Volume 434Sir Norman Lockyer Macmillan Journals Limited, 2005 - Electronic journals |
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Page 99
... domain in PLC - 1 that includes a partial pleckstrin homology ( PH ) domain - a consensus lipid - binding and protein- binding sequences . We have developed a gestalt algorithm to detect hitherto ' invisible ' PH and PH - like domains ...
... domain in PLC - 1 that includes a partial pleckstrin homology ( PH ) domain - a consensus lipid - binding and protein- binding sequences . We have developed a gestalt algorithm to detect hitherto ' invisible ' PH and PH - like domains ...
Page 100
... PH - n 51.9 % 3-102 PH - n 51.9 % 3-102 PH - c 51.0 % 2-101 PH - c 51.0 % 1-100 PH - c 51.0 % PH domain complementation ( % ) PH domain complementation ( % ) PH domain complementation ( % ) 1 100- 95 90- 85- BEACH WD40-2946 2140-2265 ...
... PH - n 51.9 % 3-102 PH - n 51.9 % 3-102 PH - c 51.0 % 2-101 PH - c 51.0 % 1-100 PH - c 51.0 % PH domain complementation ( % ) PH domain complementation ( % ) PH domain complementation ( % ) 1 100- 95 90- 85- BEACH WD40-2946 2140-2265 ...
Page 101
... PH domain consensus into each amino acid position of the target protein we essentially slide a partial PH consensus through the entire coding sequence ( Fig . 2a , cartoon ) . At each sequence - hybrid position we assess PH domain ...
... PH domain consensus into each amino acid position of the target protein we essentially slide a partial PH consensus through the entire coding sequence ( Fig . 2a , cartoon ) . At each sequence - hybrid position we assess PH domain ...
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acid activity analysis antibody antigen apoptotic apoptotic cell applications areas assays binding biodiversity Biol biology cancer candidate CD8+ T cells Cell Biology centre Clb5 cluster complex cross-presentation cyclins dendritic detected drug electron emission encoded error experience expression function gap junctions GCRT gene genetic genome helpless CD8+ human HutP hydrogenosomes images indicated infection Institute interactions Izumo kinase laboratory levels ligand males measured mechanism mice mitochondrial molecular molecules monocytes mRNA mutant nanoparticles Nature nature publishing group Naturejobs observed ovalis peptide PGC-la PH domain PH-c phosphorylation Phys programme protein pyruvate quantum computing qubits radiolarites receptor region samples SCAN1 Science scientists sequence shown signalling siRNA SIRT1 sonoluminescence specific sperm structure substrates Supplementary Fig Supplementary Information Supplementary Table surface target TDP1 temperature transcription TRPC3 University wild-type XRCC1