Nature, Volume 456Sir Norman Lockyer Macmillan Journals Limited, 2008 - Electronic journals |
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Page 338
... region A , and a site in DVI is bound by CID region C. In this way , CIDs bind simultaneously to two widely sepa- rated domains of calpain . This strong binding allows CID region B- a largely unstruc- tured area between the helices ...
... region A , and a site in DVI is bound by CID region C. In this way , CIDs bind simultaneously to two widely sepa- rated domains of calpain . This strong binding allows CID region B- a largely unstruc- tured area between the helices ...
Page 404
... Region B associates with DI - III to obstruct the active site in the extended substrate - like orientation . Intrinsic disorder in the free state enables calpastatin to adapt structurally on binding to the substrate - binding cleft of ...
... Region B associates with DI - III to obstruct the active site in the extended substrate - like orientation . Intrinsic disorder in the free state enables calpastatin to adapt structurally on binding to the substrate - binding cleft of ...
Page 405
... regions A and C interact with calpain whereas the intervening regions are disordered1 . Notably , calpastatin region B corresponding to Lys 176 - Leu 188 , which in our complex targets mainly DI , also interacts with calpain . At this ...
... regions A and C interact with calpain whereas the intervening regions are disordered1 . Notably , calpastatin region B corresponding to Lys 176 - Leu 188 , which in our complex targets mainly DI , also interacts with calpain . At this ...
Contents
53 | 1 |
Xavier R J Podolsky D K Unravelling the pathogenesis of inflammatory bowel requests for materials should be addressed to H W V virginwustl edu | 7 |
73 | 56 |
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activity analysis APOBEC3G applications associated autophagy behaviour Biol biology brain calpain cancer candidates cell biology Center changes channel chromatin chromosome climate complex corneal CRTC2 dark matter detected diatoms disease DNA methylation domain dynamics e-mail effect electron emission energy experience expression function genes genetic genome sequence genotype Holliday junction human adult GSCs human genome imaging Institute interactions melanotrope Methods methylation mice molecular molecules mutations nanowires Nature nature publishing group NATUREJOBS neurons Neurosci nuclear observed optical paddle motifs Paneth cells paper at www.nature.com/nature Phys position PPAR-y predation predicted protein quantum quantum dot receptor region response Rhcg role sample says Science scientific scientists signal simulations SNPs specific stem cells structure Supplementary Fig Supplementary Information Supplementary Table target temperature tion toxin transcription tumour University variants wild-type yeast