RabiesAlan C. Jackson, William H. Wunner Rabies offers a complete account of one of the oldest known diseases threatening public health today. Unlike most research-oriented descriptions of rabies, this book provides a narrative about the disease and its etiologic agent, encompassing the historical background to recent developments. The emphasis on the basic biology and molecular virology of the disease is intended to convey an understanding of the underlying mechanisms involved in the disease - essential information for diagnosis and prevention strategies. Current methods used in defining geographic origins and animal species of rabies viruses in wildlife are presented, along with diagnostic methods for identifying the strain of virus based on its genomic sequence and antigenic structure. The latest approved methods for controlling rabies in wildlife species are also covered. This account of rabies will interest clinicians, public health advisors, epidemiologists, research scientists, and anyone involved in diagnosing, treating, controlling, and preventing this disease. Key Features* A history of rabies from antiquity to the modern era* Basic biology and molecular virology* Epidemiological aspects* Pathogenesis and pathology of the disease* Clinical manifestations and diagnostic evaluation in humans and animals* Preventive measures in humans and animals |
Contents
| 1 | |
| 23 | |
Chapter 3 Molecular Epidemiology | 79 |
Chapter 4 Epidemiology | 113 |
Chapter 5 Animal Rabies | 163 |
Chapter 6 Human Disease | 219 |
Chapter 7 Pathogenesis | 245 |
Chapter 8 Pathology | 283 |
Chapter 9 Diagnostic Evaluation | 307 |
Other editions - View all
Rabies: Scientific Basis of the Disease and Its Management William H. Wunner,Alan C. Jackson Limited preview - 2010 |
Common terms and phrases
acid activity America animals antibody antigen appear areas associated Baer bait binding bite bodies brain canine cats cell culture cells Centers central changes clinical complex countries coyotes culture cytoplasm death detected developed diagnosis disease dogs domestic early effective epidemiology et al experimental exposure expression gene genetic genome glycoprotein History host human rabies immune important increased indicate initial inoculation involved isolates Jackson Koprowski laboratory lyssavirus major membrane methods mice molecular Natural neurons observed occur oral Organization patients period population positive possible Prevention produced programs protection protein public health rabid rabies vaccine rabies virus rabies virus infection raccoons receptor region replication reported reservoir response saliva samples sequence skunks Smith species spread strain structure studies suggest Table tion tissue transcription transmission treatment United viral virions Virol virus variant viruses wildlife World
Popular passages
Page 399 - Wiktor, TJ, MacFarlan, RI, Reagan, KJ, Dietzschold, B., Curtis, PJ, Wunner, WH, Kieny, MP, Lathe, R., Lecocq, JP, Mackett, M., Moss, B. and Koprowski, H., 1984, Protection from rabies by a vaccinia virus recombinant containing the rabies virus glycoprotein gene, Proc.
Page 393 - Brochier, B., Kieny, MP, Costy, F., Coppens, P., Bauduin, B., Lecocq, JP, Languet, B., Chappuis, G., Desmettre, P., Afiademanyo, K., Libois, R., and Pastoret, P.-P.
Page 478 - Human rabies prevention — United States. 1999. Recommendations of the Advisory Committee on Immunization Practices (ACIP).
Page 479 - Koprowski, H. (1997). Antigens produced in plants by infection with chimeric plant viruses immunize against rabies virus and HIV-1. Proc. Natl. Acad. Sci. USA 94, 5784-5788.