Molecular Biology: Structure and Dynamics of Genomes and Proteomes

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Garland Science, Nov 23, 2015 - Science - 648 pages
Recipient of the CHOICE Outstanding Academic Title (OAT) Award.Molecular Biology: Structure and Dynamics of Genomes and Proteomes illustrates the essential principles behind the transmission and expression of genetic information at the level of DNA, RNA, and proteins.This textbook emphasizes the experimental basis of discovery and the most recent a
 

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Contents

To the Cell and Beyond The Realm of Molecular Biology
1
From Classical Genetics to Molecular Genetics
15
Proteins
31
Nucleic Acids
65
Recombinant DNA Principles and Applications
93
ProteinNucleic Acid Interactions
127
The Genetic Code Genes and Genomes
145
Physical Structure of the Genomic Material
163
Transcription Regulation in the Human Genome
297
RNA Processing
315
Translation The Players
347
Translation The Process
371
Regulation of Translation
395
Protein Processing and Modification
421
DNA Replication in Bacteria
457
DNA Replication in Eukaryotes
485

Transcription in Bacteria
193
Transcription in Eukaryotes
215
Regulation of Transcription in Bacteria
241
Regulation of Transcription in Eukaryotes
261
DNA Recombination
515
DNA Repair
549
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About the author (2015)

Jordanka Zlatanova is Professor Emeritus in the Department of Molecular Biology at the University of Wyoming. She earned her PhD and DSc degrees in cellular and molecular biology from the Bulgarian Academy of Sciences, conducting experiments at the Ernst Boehringer Institute for Drug Research in Vienna, Austria. Zlatanova was Department Head of the Molecular Genetics at the Institute of Genetics in the Bulgarian Academy of Sciences before becoming a Senior Research Professor at Oregon State University. She was also Deputy Director of the Biochip Center at Argonne National Laboratory and a Professor in the Department of Chemical and Biological Sciences and Engineering at Polytechnic University in Brooklyn, NY. Zlatanova is a member of the Bulgarian Union of Scientists, Biochemistry and Biophysics Section, the Austrian Biochemical Society, and the International Society for Plant Molecular Biology and was the recipient of an International Cancer Research Technology Transfer (ICRETT) Award. She has authored over 150 papers and numerous books and book chapters. Her research interests are in chromatin structure and dynamics and its role in transcription regulation.

Kensal E. van Holde is Distinguished Professor Emeritus in the Department of Biochemistry and Biophysics at Oregon State University. He earned his PhD in physical chemistry at the University of Wisconsin, Madison. After working as an industrial chemist, he returned to academia and in 1967, he joined the Department of Biochemistry and Biophysics at Oregon State University, reflecting his evolving interests from polymer chemistry to biology. van Holde has won numerous teaching and education awards, and is a fellow of the American Association for the Advancement of Science (AAAS) and member of the American Academy of Arts and Sciences and the National Academy of Science. His research has focused on the structure and functi

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