The Microbe-Host Interface in Respiratory Tract InfectionsJan L. L. Kimpen, Octavio Ramilo The molecular pathogenesis of microbial agents responsible for respiratory tract infections (RTIs) has been the focus of much research in recent years. The emphasis has been on developing new treatments such as novel antimicrobials and more effective vaccines. Significant attention has also been paid to improving molecular diagnostic methods to identify RTI-causing microbes, as well as understanding the host response to them. The Microbe-Host Interface in Respiratory Tract Infections presents an overview of the current knowledge in this area. It provides us with the first coherent picture of emerging strategies for controlling the microbes responsible for RTIs. This comprehensive volume is divided into three sections: the first reviews topics of general interest; the second focuses on bacterial and atypical RTIs; while the final section covers viral RTIs. Each of the chapters is the work of two or more of the top scientists in the field writing about their own pioneering research. Various chapters comment on vaccines, antibiotics, and molecular diagnostic methods. This cutting-edge work is essential reading for research microbiologists and other scientists involved in the investigation and treatment of RTIs. |
Contents
The Role of Microbes | 31 |
New Diagnostic Modalities In Respiratory Tract Disease | 95 |
The Pathogenesis of Bacterial Respiratory Tract Infection | 109 |
The Role of Atypical Agents in Respiratory Tract Disease | 133 |
Antibiotic Treatment of Lower Respiratory Tract Infection | 193 |
Vaccines in the Prevention of Bacterial Respiratory Tract | 213 |
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The Microbe-Host Interface in Respiratory Tract Infections Jan L. L. Kimpen,Octavio Ramilo Limited preview - 2004 |
Common terms and phrases
acute otitis media adenovirus infection adults aeruginosa agents airway Allergy allogeneic antibiotics antibody antigen antimicrobial AOM episodes associated asthma atopic disease aureus bacterial bone marrow transplantation bronchiolitis cause cepacia Chlamydia pneumoniae chronic Clin clinical colonisation common community-acquired pneumonia culture cystic fibrosis cytokine detection diagnosis effect epidemiological epithelial cells exacerbations gene genetic Haemophilus influenzae hospitalized host human hygiene hypothesis immune response immunocompromised immunodeficiency immunoglobulin Immunol immunosuppressive increased induced infants inflammatory isolated lower respiratory tract LRTI lymphocytes macrolides macrophages mice Microbiol molecular Mycobacterium Mycoplasma pneumoniae nasopharyngeal nosocomial organisms otitis media pathogenesis pathogens patients Pediatr pneumococcal conjugate vaccine pneumoniae infection pneumophila polymorphisms prevention protein Pseudomonas pulmonary receptor resistance Respir respiratory infections respiratory syncytial virus respiratory tract infections rhinovirus rhinovirus infection risk factors role RSV infection serotypes serum specific strains Streptococcus pneumoniae studies susceptibility T-cells therapy tissue treatment tuberculosis viral infections Virol viruses wheezing