Chronic Infection, Chlamydia and Coronary Heart DiseaseCoronary heart disease (CHD) remains a major cause of human mortality and morbidity worldwide. Classical risk factors for atherosclerosis fail to account fully for the wide variations in CHD prevalence and/or severity between differing populations. The search for hitherto unrecognised risk factors has recently focused on the potential role of chronic inflammation and common infections. Chronic Infection, Chlamydia and Coronary Heart Disease is the first book to review the wealth of evidence linking various infective agents with CHD, focusing particularly on the proposed pathogenetic role of the main candidate microorganism, Chlamydia pneumoniae. Written by two leading investigators in the field, the book provides a concise, clearly written and up-to-date account of the diverse lines of evidence - seroepidemiological, pathological, animal and in vitro data and clinical antibiotic trials. The possibility of an infective basis to atherosclerosis and CHD has already attracted much scientific interest. Chronic Infection, Chlamydia and Coronary Heart Disease highlights the key published works on the topic, and concludes with information on existing, ongoing, and future lines of enquiry. |
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Chronic Infection, Chlamydia and Coronary Heart Disease S. Gupta,A.J. Camm No preview available - 2014 |
Chronic Infection, Chlamydia and Coronary Heart Disease S. Gupta,A.J. Camm No preview available - 1999 |
Common terms and phrases
activation acute coronary angiographically anti-C anti-chlamydial antibiotic antigen aorta aortic association atherectomy atherogenesis atherogenic atheromatous plaques atherosclerosis atherosclerotic disease atherosclerotic lesions atherosclerotic plaques azithromycin C-reactive protein cardiac cardiovascular disease cardiovascular events cardiovascular risk factors carotid Chlamydia pneumoniae Chlamydia pneumoniae infection chlamydial infection cholesterol chronic infection Clin Microbial clinical Coll Cardiol controls coronary artery disease coronary heart disease coronary syndromes cytokine cytomegalovirus demonstrated dental detected elevated endothelial cells endothelium evidence fibrinogen findings first foam cell Grayston JT Helicobacter pylori human hypertension increased infection with Chlamydia infections and coronary inflammation inflammatory investigators ISBN ischaemic Lancet leucocyte levels lipid macrolide macrophages markers Mendall microimmunofluorescence monocytes neopterin odds ratio organism pneumoniae antibody titres potential presence prevalence procoagulant randomised role roxithromycin Saikku serological seropositivity serum significantly smoking smooth muscle cells specimens strain TWAR suggested therapy tissue factor trachomatis transplant unstable angina vascular virus vitro Wang SP