NatureSir Norman Lockyer Macmillan Journals Limited, 2007 - Science |
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Page 45
... CD1d - restricted interaction ( Fig . 1d ) . Accordingly , the salient fea- tures of MHC - peptide - mediated recognition by a TCR are not pre- served in CD1d - lipid - mediated recognition . NKT TCR - CD1d interaction The human NKT TCR ...
... CD1d - restricted interaction ( Fig . 1d ) . Accordingly , the salient fea- tures of MHC - peptide - mediated recognition by a TCR are not pre- served in CD1d - lipid - mediated recognition . NKT TCR - CD1d interaction The human NKT TCR ...
Page 46
... CD1d cross - reactivity correlates with the high level of sequence similarity in the CDR2ẞ loops of mouse Vẞ8.2 and human Vẞ11 ( Supplementary Fig . 3 ) . In contrast , rat NKT cells are restricted to their syngeneic CD1d - a - GalCer ...
... CD1d cross - reactivity correlates with the high level of sequence similarity in the CDR2ẞ loops of mouse Vẞ8.2 and human Vẞ11 ( Supplementary Fig . 3 ) . In contrast , rat NKT cells are restricted to their syngeneic CD1d - a - GalCer ...
Page 47
... CD1d - a - GalCer com- plexes ( and vice versa ) with approximately comparable affinity ' , highlighting the evolutionarily conserved nature of this interaction . Of the interactions mediated by CD1d , only three ( positions 84 , 89 and ...
... CD1d - a - GalCer com- plexes ( and vice versa ) with approximately comparable affinity ' , highlighting the evolutionarily conserved nature of this interaction . Of the interactions mediated by CD1d , only three ( positions 84 , 89 and ...
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activity adhesive analysis applications beam binding Biol biology boson brain Ca2+ calmodulin carbon CD1d CDNF CERN channel clones collisions complex density detected detector ecosystem electron energy epiblast EpiSCs experiments expression factors function gene genetic genome Hadron Higgs Higgs boson human imaging Institute interactions iPS cells Laboratory Large Hadron Collider levels magnetic measurements mechanism methylation mice mimics molecular mouse ES cells mutant Nanog Nanog iPS Nature nature publishing group naturejobs neurons observed Oct4 paper at www.nature.com/nature particles peptide photon Phys physics plants pluripotent position potential production protein quantum quark-gluon plasma quarks receptor RNAi RNAP scientific scientists sequence signalling silicon siRNA Sox2 species standard model stem cells structure substrate supercoils Supplementary Fig Supplementary Information Supplementary Table surface target temperature theory tion topotecan transcription transform fault transgenic TRPM8 University wild-type