NatureSir Norman Lockyer Macmillan Journals Limited, 2007 - Science |
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Page 87
... methylation as a stable epigenetic marker . However , little is known about how the demethylases are selective for particular lysyl - containing sequences in specific methylation states , a key to understanding their functions . Here we ...
... methylation as a stable epigenetic marker . However , little is known about how the demethylases are selective for particular lysyl - containing sequences in specific methylation states , a key to understanding their functions . Here we ...
Page 320
... methylation mark and the ' repressive ' histone H3 lysine 27 ( H3K27 ) methylation mark13,14 . In differentiated cells , those genes tend instead to carry either H3K4 or H3K27 methylation depending on their expression state . We used ...
... methylation mark and the ' repressive ' histone H3 lysine 27 ( H3K27 ) methylation mark13,14 . In differentiated cells , those genes tend instead to carry either H3K4 or H3K27 methylation depending on their expression state . We used ...
Page 716
... methylation . Under this model , DNMT3L triggers de novo DNA methylation by activation or recruitment of DNMT3A2 upon contact with nucleosomes that contain unmethylated H3 lysine 4 , while other sequences are masked from DNMT3L by the ...
... methylation . Under this model , DNMT3L triggers de novo DNA methylation by activation or recruitment of DNMT3A2 upon contact with nucleosomes that contain unmethylated H3 lysine 4 , while other sequences are masked from DNMT3L by the ...
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