Protein Targeting with Small Molecules: Chemical Biology Techniques and Applications
Discover the link between the latest chemical biology approaches and novel drug therapies!
Protein Targeting with Small Molecules: Chemical Biology Techniques and Applications takes readers beyond the use of chemical biology in basic research, providing a highly relevant look at techniques that can address the challenges of biology and drug design and development.
This indispensable bench companion features up-to-date coverage of advances in chemistry and assesses their impact on developing new therapeutics, making it ideal for chemical biologists and medicinal chemists who are developing small molecule drugs to target proteins and treat diseases. In addition, the book examines the full range of complex biological systems and their interrelationship with chemistry, from the interaction of biological response modifiers with proteins to the chemical biology of cell surface oligosaccharides.
Distinguished by an overview of chemical biology that is reinforced and clarified by detailed examples and descriptions of techniques, Protein Targeting with Small Molecules: Chemical Biology Techniques and Applications:
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2 Target Profiling of Small Molecules
3 Novel Applications of Affinity Beads
4 Recent Developments and Advances in Chemical Arrays
5 Use of the Phage Display Technique to Identify the Target Protein
6 Development of Fluorescent Probes for Small Molecules
7 Development of SmallMolecule Ligands and Inhibitors
8 Interaction of a Biological Response Modifier with Proteins
9 Chemical Biology of Cell Motility Inhibitors
10 Chemical Biology of Cell Surface Oligosaccharides
11 Chemical Genomics Based on Yeast Genetics
12 Data on Small Molecules and Their Target Proteins