Handbook of Radiopharmaceuticals: Radiochemistry and ApplicationsMichael J. Welch, Carol S. Redvanly A comprehensive, authoritative and up-to-date reference for the newcomer to radiopharmaceuticals and those already in the field. Radiopharmaceuticals are used to detect and characterise disease processes, or normal biological function, in living cells, animals or humans. Used as tracer molecules, they map the distribution, uptake and metabolism of the molecule in clinical studies, basic research or applied research. The area of radiopharmaceuticals is expanding rapidly. The number of PET centers in the world is increasing at 20% per year, and many drug companies are utilising PET and other forms of radiopharmaceutical imaging to evaluate products. * Readers will find coverage on a number of important topics such as radionuclide production, PET and drug development, and regulations * Explains how to use radiopharmaceuticals for the diagnosis and therapy of cancer and other diseases * The editors and a majority of the contributors are from the United States |
Contents
Accelerators Available for Isotope Production | 71 |
Reactor Production of Radionuclides | 87 |
Chemistry of Nitrogen13 and Oxygen15 | 119 |
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affinity analogs antibody Appl applications Applied Radiation Isotopes automated biodistribution Biol blood flow brain bromine cancer carbon cells chelate Chem chemical clinical cocaine complex cyclotron decay dopamine dopamine transporter dose drug electron electrophilic energy evaluation fluorine fluorine-18 Fowler function gamma gene half-life high specific activity human imaging agents injection International Journal iodide iodine irradiation Isot Isotopes Katzenellenbogen kinetic Labelled Compd Långström ligands metabolism method Mirzadeh molecule myocardial neutron nitrogen-13 no-carrier-added Nucl Nuclear Medicine nuclear reactions nucleophilic octreotide oxide particle patients peptide PET studies plasma positron emission tomography potential precursor prepared Production Reactions protein proton Qaim SM Radiation and Isotopes radioactive radiochemical Radiochimica Acta radioiodine radioisotopes radiolabeled radioligand radionuclides Radiopharm radiopharmaceuticals radiotracer reactor reagents serotonin somatostatin synthesis Target Chemistry target material Targetry and Target technetium therapy tissue tracer tumor uptake vitro vivo Volkow Welch MJ Wolf AP Workshop on Targetry yield