Nature, Volume 448Sir Norman Lockyer Macmillan Journals Limited, 2007 - Electronic journals |
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Page 44
... CD1d . NKT - cell - mediated recognition of the CD1d - antigen complex has been implicated in microbial immunity , tumour immunity , autoimmunity and allergy . Here we describe the structure of a human NKT TCR in complex with CD1d bound ...
... CD1d . NKT - cell - mediated recognition of the CD1d - antigen complex has been implicated in microbial immunity , tumour immunity , autoimmunity and allergy . Here we describe the structure of a human NKT TCR in complex with CD1d bound ...
Page 45
... CD1d - restricted interaction ( Fig . 1d ) . Accordingly , the salient fea- tures of MHC - peptide - mediated recognition by a TCR are not pre- served in CD1d - lipid - mediated recognition . NKT TCR - CD1d interaction The human NKT TCR ...
... CD1d - restricted interaction ( Fig . 1d ) . Accordingly , the salient fea- tures of MHC - peptide - mediated recognition by a TCR are not pre- served in CD1d - lipid - mediated recognition . NKT TCR - CD1d interaction The human NKT TCR ...
Page 46
... CD1d cross - reactivity correlates with the high level of sequence similarity in the CDR2ẞ loops of mouse Vẞ8.2 and human Vẞ11 ( Supplementary Fig . 3 ) . In contrast , rat NKT cells are restricted to their syngeneic CD1d - a - GalCer ...
... CD1d cross - reactivity correlates with the high level of sequence similarity in the CDR2ẞ loops of mouse Vẞ8.2 and human Vẞ11 ( Supplementary Fig . 3 ) . In contrast , rat NKT cells are restricted to their syngeneic CD1d - a - GalCer ...
Contents
Crinan St London N1 9XW | 4 |
Abbott | 14 |
How T cells recognize sugars | 27 |
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activity adhesive analysis applications beam binding Biol biology boson brain calmodulin CD1d CDNF CERN channel clones collisions complex density detected detector e-mail ecosystem effects electron energy epiblast EpiSCs experiments expression factors function gene genetic genome Hadron Higgs Higgs boson human imaging Institute interactions iPS cells Laboratory Large Hadron Collider levels Lsi2 magnetic measurements mechanism methylation mice mimics molecular mouse ES cells mutant Nanog Nanog iPS nature publishing group Naturejobs neurons observed Oct4 paper at www.nature.com/nature particles peptide photon Phys physics plants pluripotent position potential protein quantum quark-gluon plasma quarks Rab8 receptor RNAi RNAP scientific scientists sequence signalling silicon siRNA Sox2 species standard model stem cells structure substrate supercoils Supplementary Fig Supplementary Information Supplementary Table surface target temperature theory tion topotecan transcription transform fault transgenic TRPM8 University wild-type