Nature, Volume 448Sir Norman Lockyer Macmillan Journals Limited, 2007 - Electronic journals |
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Page 163
... substrate analogue , adenosine - 5 ' - [ ( a , ẞ ) -methyleno ] -triphosphate ( AMPCPP ) , and with AMPCPP plus the inhibitor streptolydigin . In the EC / AMPCPP structure , the substrate binds to the active ( ' insertion ' ) site ...
... substrate analogue , adenosine - 5 ' - [ ( a , ẞ ) -methyleno ] -triphosphate ( AMPCPP ) , and with AMPCPP plus the inhibitor streptolydigin . In the EC / AMPCPP structure , the substrate binds to the active ( ' insertion ' ) site ...
Page 165
... substrate phosphates is stabilized through 11 hydrogen bonds with six basic residues , among which four were predicted from the yeast EC structure and modelling of the bacterial substrate complex ' ; the other two , Arg B'1239 and His B ...
... substrate phosphates is stabilized through 11 hydrogen bonds with six basic residues , among which four were predicted from the yeast EC structure and modelling of the bacterial substrate complex ' ; the other two , Arg B'1239 and His B ...
Page 167
... Substrate loading occurs in two steps . First , the NTP binds to the open EC to form an inactive , preinsertion intermediate , working as a ' ratchet ' that stabilizes the post - translocated EC30 and providing the first sieve for substrate ...
... Substrate loading occurs in two steps . First , the NTP binds to the open EC to form an inactive , preinsertion intermediate , working as a ' ratchet ' that stabilizes the post - translocated EC30 and providing the first sieve for substrate ...
Contents
Crinan St London N19XW | 4 |
How T cells recognize sugars | 27 |
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