Nature, Volume 448Sir Norman Lockyer Macmillan Journals Limited, 2007 - Electronic journals |
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Page 199
... wild - type ganglia . Thus TRPM8 ablation results in a profound reduction in both the number and magnitude of cellular cold responses , leaving intact a small cohort of neurons that respond to cold with an activation threshold of ~ 12 ...
... wild - type ganglia . Thus TRPM8 ablation results in a profound reduction in both the number and magnitude of cellular cold responses , leaving intact a small cohort of neurons that respond to cold with an activation threshold of ~ 12 ...
Page 200
... wild - type litter- mates ( Fig . 4a ) . Next , we asked whether these animals also exhibit deficits in their ability to discriminate between warm and cold 60- 50 Neurons ( % ) Mustard 40- oil Menthol Icilin 30- *** *** 20 TRPM8 + / + ...
... wild - type litter- mates ( Fig . 4a ) . Next , we asked whether these animals also exhibit deficits in their ability to discriminate between warm and cold 60- 50 Neurons ( % ) Mustard 40- oil Menthol Icilin 30- *** *** 20 TRPM8 + / + ...
Page 498
... wild - type plants when tested with appropriate primers by PCR with reverse transcrip- tion ( RT - PCR ; Fig . 1c ) or by northern blot analysis ( Supplementary Fig . 1 ) . Complementation of bakl mutants with wild - type BAKI restored ...
... wild - type plants when tested with appropriate primers by PCR with reverse transcrip- tion ( RT - PCR ; Fig . 1c ) or by northern blot analysis ( Supplementary Fig . 1 ) . Complementation of bakl mutants with wild - type BAKI restored ...
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activity adhesive analysis applications beam binding Biol biology boson brain calmodulin CD1d CDNF CERN channel clones collisions complex density detected detector e-mail ecosystem effects electron energy epiblast EpiSCs experiments expression factors function gene genetic genome Hadron Higgs Higgs boson human imaging Institute interactions iPS cells Laboratory Large Hadron Collider levels Lsi2 magnetic measurements mechanism methylation mice mimics molecular mouse ES cells mutant Nanog Nanog iPS nature publishing group Naturejobs neurons observed Oct4 paper at www.nature.com/nature particles peptide photon Phys physics plants pluripotent position potential protein quantum quark-gluon plasma quarks Rab8 receptor RNAi RNAP scientific scientists sequence signalling silicon siRNA Sox2 species standard model stem cells structure substrate supercoils Supplementary Fig Supplementary Information Supplementary Table surface target temperature theory tion topotecan transcription transform fault transgenic TRPM8 University wild-type