An Introduction to Genetic EngineeringIn this third edition of his popular undergraduate-level textbook, Des Nicholl recognises that a sound grasp of basic principles is vital in any introduction to genetic engineering. Therefore, the book retains its focus on the fundamental principles used in gene manipulation. It is divided into three sections: Part I provides an introduction to the relevant basic molecular biology; Part II, the methods used to manipulate genes; and Part III, applications of the technology. There is a new chapter devoted to the emerging importance of bioinformatics as a distinct discipline. Other additional features include text boxes, which highlight important aspects of topics discussed, and chapter summaries, which include aims and learning outcomes. These, along with key word listings, concept maps and a glossary, will enable students to tailor their study to suit their own learning styles and ultimately gain a firm grasp of a subject that students traditionally find difficult. |
Contents
5 | |
11 | |
x | 17 |
viii | 23 |
Working with nucleic acids | 32 |
vi | 40 |
The tools of the trade | 50 |
The methodology of gene manipulation | 61 |
Bioinformatics | 152 |
Genetic engineering in action | 169 |
Genetic engineering and biotechnology | 202 |
Medical and forensic applications of gene | 226 |
Transgenic plants and animals | 256 |
The other sort of cloning | 278 |
Brave new world or genetic nightmare? | 291 |
Suggestions for further reading | 297 |
Other editions - View all
An Introduction to Genetic Engineering International Student Edition Desmond S. T. Nicholl No preview available - 2008 |
Common terms and phrases
achieved activity addition analysis applications approach aspects bacterial bacteriophage base basic become biology called carried cDNA cells Chapter chromosome cloning coli complex considered construction contain copy database describe determined digestion DNA fragments DNA molecules DNA sequencing effect enable ends engineering enzyme essential eukaryotic example experiments expression first function further gene gene manipulation genetic genome give host cell human important insert involved isolated known labelled major mapping method molecular molecules mRNA nucleic acid organism particular phage plant plasmid polymerase possible preparation present primer probe problems procedure production projects promoter protein range reaction recombinant recombinant DNA region relatively removed replacement represent restriction restriction enzyme result RNAi screening selection single specific stage strand structure suitable synthesis Table techniques tion transcription transgenic translation usually various vectors
Popular passages
Page 6 - Drosophila, was seen in an entirely new light following the discovery of the structure of DNA by James Watson and Francis Crick in 1953.