Forensic DNA Typing: Biology, Technology, and Genetics of STR Markers

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Elsevier, Feb 8, 2005 - Social Science - 688 pages

Forensic DNA Typing, Second Edition, is the only book available that specifically covers detailed information on mitochondrial DNA and the Y chromosome. It examines the science of current forensic DNA typing methods by focusing on the biology, technology, and genetic interpretation of short tandem repeat (STR) markers, which encompass the most common forensic DNA analysis methods used today.

The book covers topics from introductory level right up to cutting edge research. High-profile cases are addressed throughout the text, near the sections dealing with the science or issues behind these cases. Ten new chapters have been added to accommodate the explosion of new information since the turn of the century. These additional chapters cover statistical genetic analysis of DNA data, an emerging field of interest to DNA research. Several chapters on statistical analysis of short tandem repeat (STR) typing data have been contributed by Dr. George Carmody, a well-respected professor in forensic genetics. Specific examples make the concepts of population genetics more understandable.

This book will be of interest to researchers and practitioners in forensic DNA analysis, forensic scientists, population geneticists, military and private and public forensic laboratories (for identifying individuals through remains), and students of forensic science.

*The only book available that specifically covers detailed information on mitochondrial DNA and the Y chromosome*Chapters cover the topic from introductory level right up to "cutting edge" research*High-profile cases are addressed throughout the book, near the sections dealing with the science or issues behind these cases*NEW TO THIS EDITION: D.N.A. Boxes--boxed "Data, Notes & Applications" sections throughout the book offer higher levels of detail on specific questions
 

Contents

1 OVERVIEW AND HISTORY OF DNA TYPING
1
BIOLOGY
15
TECHNOLOGY
311
GENETICS
453
BIOLOGY TECHNOLOGY AND GENETICS
539
SIZES AND SEQUENCES
561
APPENDIX II US POPULATION DATA STR ALLELE FREQUENCIES
577
APPENDIX III SUPPLIERS OF DNA ANALYSIS EQUIPMENT PRODUCTS OR SERVICES
585
APPENDIX IV DNA ADVISORY BOARD QUALITY ASSURANCE STANDARDS
593
APPENDIX V DAB RECOMMENDATIONS ON STATISTICS
613
APPENDIX VI NRC II RECOMMENDATIONS
623
APPENDIX VII EXAMPLE DNA CASES
627
AUTHOR INDEX
633
SUBJECT INDEX
647
Copyright

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About the author (2005)

John M. Butler is a NIST Fellow and Special Assistant to the Director for Forensic Science, Office of Special Programs, at the U.S. National Institute of Standards and Technology, in Gaithersburg, Maryland. Dr. Butler earned his PhD from the University of Virginia while doing DNA research in the FBI Laboratory's Forensic Science Research Unit. He has won numerous scientific awards, including being named Science Watch’s #1 world-wide high-impact author in legal medicine and forensic science over the last decade (July 2011). He has over 150 publications in this field and is a frequent presenter on the topic of DNA typing, and has authored four other DNA Typing books including Advanced Topics in Forensic DNA Typing: Methodology. For a detailed CV, visit http://www.cstl.nist.gov/strbase/butler.htm.

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