Emerging Concepts in Bacterial Biofilms: Molecular Mechanisms and Control Strategies

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Cambridge Scholars Publisher, 2020 - Biofilms - 381 pages
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The ability to form biofilms is a universal attribute of bacteria. Bacteria are able to grow on almost every surface, forming these architecturally complex communities. In biofilms, the cells grow in multicellular aggregates, encased in an extracellular matrix produced by the bacteria themselves. They impact humans in many ways, and can form in natural, medical and industrial settings. For example, the formation of biofilms on medical devices such as catheters or implants often results in difficult-to-treat chronic infections. This book focuses on emerging concepts in bacterial biofilm research, such as the different mechanisms of biofilm formation in Gram negative and Gram positive bacteria, and the burden of biofilm associated infections. It also highlights the various anti-biofilm strategies that can be translated to curb biofilm-associated infections and the escalation of antimicrobial resistance determinants.

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About the author (2020)

Dr Sabu Thomas heads the Cholera and Biofilm Research Group at the Rajiv Gandhi Centre for Biotechnology, India. He has more than two decades‚e(tm) research experience in environmental and clinical pathogen biology with a special focus on diarrhoeal pathogens, antimicrobial resistance and alternative strategies in curbing bacterial infections. He has more than 75 publications to his credit in various national and international journals, as well as 12 book chapters. Currently, he is a member of the Global Task Force on Cholera Control of the World Health Organization and the State Working Committee on Antimicrobial Resistance of the Government of Kerala, India.

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